Evidence map›Paper›PMID 35057095›Full record

ArticlePharmaceutics2022

DELOS Nanovesicles-Based Hydrogels: An Advanced Formulation for Topical Use.

Lídia Ballell-Hosa, Elisabet González-Mira, Hector Santana, Judit Morla-Folch, Marc Moreno-Masip, Yaima Martínez-Prieto, Albert Revuelta, Primiano Pio Di Mauro, Jaume Veciana, Santi Sala and 2 more

Abstract read
In one paragraph

Article in Pharmaceutics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
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  5. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Lídia Ballell-HosaNanomol Technologies S.L., 08193 Cerdanyola del Vallès, Spain.
Elisabet González-MiraInstitut de Ciència de Materials de Barcelona (ICMAB-CSIC), 08193 Bellaterra, Spain.
Hector SantanaCenter for Genetic Engineering and Biotechnology (CIGB), 31st Avenue between 158 and 190 Streets, Cubanacán, Playa, Havana 10600, Cuba.ORCID 0000-0002-2149-0921
Judit Morla-FolchInstitut de Ciència de Materials de Barcelona (ICMAB-CSIC), 08193 Bellaterra, Spain.ORCID 0000-0003-1059-6939
Marc Moreno-MasipInstitut de Ciència de Materials de Barcelona (ICMAB-CSIC), 08193 Bellaterra, Spain.
Yaima Martínez-PrietoCenter for Genetic Engineering and Biotechnology (CIGB), 31st Avenue between 158 and 190 Streets, Cubanacán, Playa, Havana 10600, Cuba.
Albert RevueltaInstitut de Ciència de Materials de Barcelona (ICMAB-CSIC), 08193 Bellaterra, Spain.
Primiano Pio Di MauroInstitut de Ciència de Materials de Barcelona (ICMAB-CSIC), 08193 Bellaterra, Spain.
Jaume VecianaInstitut de Ciència de Materials de Barcelona (ICMAB-CSIC), 08193 Bellaterra, Spain.ORCID 0000-0003-1023-9923
Santi SalaNanomol Technologies S.L., 08193 Cerdanyola del Vallès, Spain.
Lidia Ferrer-TasiesNanomol Technologies S.L., 08193 Cerdanyola del Vallès, Spain.ORCID 0000-0001-5788-3172
Nora VentosaInstitut de Ciència de Materials de Barcelona (ICMAB-CSIC), 08193 Bellaterra, Spain.ORCID 0000-0002-8008-4974

Funding

Agaur-Generalitat de Catalunya 2017-SGR-918Agaur-Generalitat de Catalunya 2018 DI 057European Union 953110European Union COMRDI15-1-0023MINECO through the Severo Ochoa Pro-gramme for Centres of Excellence in R&D CEX2019-000917-SMINECO through the Severo Ochoa Pro-gramme for Centres of Excellence in R&D SEV-2015-0496Spanish Ministry of Science and Innovation (MICINN) PID2019-105622RB-I00
6 · The paper itself

Abstract

Topical delivery has received great attention due to its localized drug delivery, its patient compliance, and its low risk for side effects. Recent developments have focused on studying new drug delivery systems as a strategy for addressing the challenges of current topical treatments. Here we describe the advances on an innovative drug delivery platform called DELOS nanovesicles for topical drug delivery. Previously, the production of DELOS nanovesicles demonstrated potentiality for the topical treatment of complex wounds, achieving well-tolerated liquid dispersions by this route. Here, research efforts have been focused on designing these nanocarriers with the best skin tolerability to be applied even to damaged skin, and on exploring the feasibility of adapting the colloidal dispersions to a more suitable dosage form for topical application. Accordingly, these drug delivery systems have been efficiently evolved to a hydrogel using Methocel

Indexed as

hydrogelnanovesiclesrheologytopical drug deliveryvesicle integrity

Identifiers

PMID35057095
PMCPMC8779640

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.