Evidence map›Paper›PMID 35057011›Full record

ArticlePharmaceutics2022

Enzymatic Synthesis and Antimicrobial Activity of Oligomer Analogues of Medicinal Biopolymers from Comfrey and Other Species of the Boraginaceae Family.

Maia Merlani, Dieter M Scheibel, Vakhtang Barbakadze, Lali Gogilashvili, Lela Amiranashvili, Athina Geronikaki, Valentina Catania, Domenico Schillaci, Giuseppe Gallo, Ivan Gitsov

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pharmaceutics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.0field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 13 citations in OpenAlex.

  1. Imidazo[2,1-Antibiotics (Basel, Switzerland) · 2026
    Article
  2. Article
  3. Review
  4. Article
  5. New Bioactive Peptides from the Mediterranean SeagrassInternational journal of molecular sciences · 2023
    Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 4 countries.

Maia MerlaniKutateladze Institute of Pharmacochemistry, Tbilisi State Medical University, 36 P.Sarajishvili Street, 0159 Tbilisi, Georgia.
Dieter M ScheibelDepartment of Chemistry, College of Environmental Science and Forestry, State University of New York, 1 Forestry Drive, Syracuse, NY 13210, USA.
Vakhtang BarbakadzeKutateladze Institute of Pharmacochemistry, Tbilisi State Medical University, 36 P.Sarajishvili Street, 0159 Tbilisi, Georgia.
Lali GogilashviliKutateladze Institute of Pharmacochemistry, Tbilisi State Medical University, 36 P.Sarajishvili Street, 0159 Tbilisi, Georgia.
Lela AmiranashviliKutateladze Institute of Pharmacochemistry, Tbilisi State Medical University, 36 P.Sarajishvili Street, 0159 Tbilisi, Georgia.
Athina GeronikakiSchool of Pharmacy, Aristotle University, 54124 Thessaloniki, Greece.ORCID 0000-0001-9894-7777
Valentina CataniaLaboratory of Microbiology and Biologic Assays, Department of Biological, Chemical and Pharmaceutical Sciences and Technologies, University of Palermo, 32 Via Archirafi, 90123 Palermo, Italy.ORCID 0000-0002-9439-0980
Domenico SchillaciLaboratory of Microbiology and Biologic Assays, Department of Biological, Chemical and Pharmaceutical Sciences and Technologies, University of Palermo, 32 Via Archirafi, 90123 Palermo, Italy.ORCID 0000-0003-2416-0474
Giuseppe GalloLaboratory of Molecular Microbiology and Biotechnology, Department of Biological, Chemical and Pharmaceutical Sciences and Technologies, University of Palermo, Viale delle Scienze, ed. 16, 90128 Palermo, Italy.ORCID 0000-0003-4727-5653
Ivan GitsovDepartment of Chemistry, College of Environmental Science and Forestry, State University of New York, 1 Forestry Drive, Syracuse, NY 13210, USA.ORCID 0000-0001-7433-8571
Tbilisi State Medical University · GEUniversity of Palermo · ITState University of New York · USAristotle University of Thessaloniki · GR

Funding

University of Palermo FFR-D15-001709
6 · The paper itself

Abstract

This study reports the first enzymatic synthesis leading to several oligomer analogues of poly[3-(3,4-dihydroxyphenyl)glyceric acid]. This biopolymer, extracted from plants of the Boraginaceae family has shown a wide spectrum of pharmacological properties, including antimicrobial activity. Enzymatic ring opening polymerization of 2-methoxycarbonyl-3-(3,4-dibenzyloxyphenyl)oxirane (MDBPO) using lipase from

Indexed as

antimicrobial activityBoraginaceae familyenzymatic polymerizationlipasepoly[3-(3,4-dihydroxyphenyl)glyceric acid]

Identifiers

PMID35057011
PMCPMC8779701
OpenAlexW4206770032

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.