Evidence map›Paper›PMID 35056988›Full record

ReviewPharmaceutics2021

Packaging and Delivery of Asthma Therapeutics.

Bryan J Mathis, Misa Kusumoto, Alexander Zaboronok, Yuji Hiramatsu

Open access · goldAbstract readReview
In one paragraph

Review in Pharmaceutics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.6field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 17 citations in OpenAlex.

  1. Review
  2. Review
  3. Nanoparticles to target asthma.American journal of physiology. Lung cellular and molecular physiology · 2024
    Review
  4. Review
  5. Review
  6. Recent Advances in Nanomaterials for Asthma Treatment.International journal of molecular sciences · 2022
    Review
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Bryan J MathisInternational Medical Center, University of Tsukuba Hospital, Tsukuba 305-8576, Japan.ORCID 0000-0002-9879-8289
Misa KusumotoSchool of Medicine, University of Tsukuba, Tsukuba 305-8575, Japan.ORCID 0000-0002-3533-302X
Alexander ZaboronokDepartment of Neurosurgery, Faculty of Medicine, University of Tsukuba, Tsukuba 305-8575, Japan.ORCID 0000-0002-6833-9866
Yuji HiramatsuInternational Medical Center, University of Tsukuba Hospital, Tsukuba 305-8576, Japan.
University of Tsukuba · JPUniversity of Tsukuba Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Asthma is a life-altering, chronic disease of heterogenous origin that features a complex interplay of immune and environmental signaling. Although very little progress has been made in prevention, diverse types of medications and delivery systems, including nanoscale systems, have been or are currently being developed to control airway inflammation and prevent exacerbations and fibrosis. These medications are delivered through mechanical methods, with various inhalers (with benefits and drawbacks) existing, and new types offering some variety in delivery. Of particular interest is the progress being made in nanosized materials for efficient penetration into the epithelial mucus layer and delivery into the deepest parts of the lungs. Liposomes, nanoparticles, and extracellular vesicles, both natural and synthetic, have been explored in animal models of asthma and have produced promising results. This review will summarize and synthesize the latest developments in both macro-(inhaler) and micro-sized delivery systems for the purpose of treating asthma patients.

Indexed as

asthmadrug packagingexosomeinhaled medicationsliposomenanoparticle

Identifiers

PMID35056988
PMCPMC8777963
OpenAlexW4205154326

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.