Evidence map›Paper›PMID 35056953›Full record

ArticlePharmaceutics2021

Solvent-Free Fabrication of Biphasic Lipid-Based Microparticles with Tunable Structure.

Serena Bertoni, Beatrice Albertini, Joanna Ronowicz-Pilarczyk, Natalia Calonghi, Nadia Passerini

Open access · goldAbstract read
In one paragraph

Article in Pharmaceutics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 11 citations in OpenAlex.

  1. Lipid Microspheres for Topical Delivery of Norfloxacin: Development and Evaluation.Recent advances in drug delivery and formulation · 2026
    Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Serena BertoniDepartment of Pharmacy and BioTechnology, Pharm Tech Lab, University of Bologna, Via S. Donato 19/2, 40127 Bologna, Italy.ORCID 0000-0002-5534-0892
Beatrice AlbertiniDepartment of Pharmacy and BioTechnology, Pharm Tech Lab, University of Bologna, Via S. Donato 19/2, 40127 Bologna, Italy.ORCID 0000-0002-9849-8593
Joanna Ronowicz-PilarczykDepartment of Inorganic and Analytical Chemistry, Faculty of Pharmacy, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Toruń, Jurasza 2, 85-089 Bydgoszcz, Poland.
Natalia CalonghiDepartment of Pharmacy and BioTechnology, Cancer Metabolism Lab, University of Bologna, Via Irnerio 48, 40126 Bologna, Italy.
Nadia PasseriniDepartment of Pharmacy and BioTechnology, Pharm Tech Lab, University of Bologna, Via S. Donato 19/2, 40127 Bologna, Italy.ORCID 0000-0002-3470-2700
University of Bologna · ITNicolaus Copernicus University · PL

Funding

Nicolaus Copernicus University IDUB 2020-1-NZ-Ronowicz
6 · The paper itself

Abstract

Lipid-based biphasic microparticles are generally produced by long and complex techniques based on double emulsions. In this study, spray congealing was used as a solvent-free fabrication method with improved processability to transform water-in-oil non-aqueous emulsions into spherical solid lipid-based particles with a biphasic structure (b-MPs). Emulsions were prepared by melt emulsification using different compositions of lipids (Dynasan

Indexed as

core-shellinterfacial tensionlong chain glyceridesmelt emulsificationmicroemulsionoral drug deliveryPEGRaman mappingspray chillingspray cooling

Identifiers

PMID35056953
PMCPMC8780016
OpenAlexW4200011108

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.