Evidence map›Paper›PMID 35056918›Full record

ArticlePharmaceutics2021

Multivesicular Liposomes for Glucose-Responsive Insulin Delivery.

Guangqu Liu, Suping He, Yu Ding, Cai Chen, Qingchun Cai, Wei Zhou

Abstract read
In one paragraph

Article in Pharmaceutics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Fabrication of vitamin BInternational journal of pharmaceutics: X · 2026
    Article
  2. Review
  3. Review
  4. Review
  5. Review
  6. Review
  7. Review
  8. Advances in Nanomedicine for Precision Insulin Delivery.Pharmaceuticals (Basel, Switzerland) · 2024
    Review
  9. Article
  10. Review
  11. Review
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Guangqu LiuDepartment of Pharmaceutics, China Pharmaceutical University, Nanjing 211198, China.
Suping HeDepartment of Pharmaceutics, China Pharmaceutical University, Nanjing 211198, China.
Yu DingDepartment of Pharmaceutics, China Pharmaceutical University, Nanjing 211198, China.
Cai ChenDepartment of Pharmaceutics, China Pharmaceutical University, Nanjing 211198, China.
Qingchun CaiDepartment of Pharmaceutics, China Pharmaceutical University, Nanjing 211198, China.
Wei ZhouDepartment of Pharmaceutics, China Pharmaceutical University, Nanjing 211198, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

An intelligent insulin delivery system is highly desirable for diabetes management. Herein, we developed a novel glucose-responsive multivesicular liposome (MVL) for self-regulated insulin delivery using the double emulsion method. Glucose-responsive MVLs could effectively regulate insulin release in response to fluctuating glucose concentrations in vitro. Notably, in situ released glucose oxidase catalyzed glucose enrichment on the MVL surface, based on the combination of (3-fluoro-4-((octyloxy)carbonyl)phenyl)boronic acid and glucose. The outer MVL membrane was destroyed when triggered by the local acidic and H

Indexed as

Alizarin red probeglucose-responsivein situ catalysisinsulinmolecular dockingMVL

Identifiers

PMID35056918
PMCPMC8781467

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.