Evidence map›Paper›PMID 35056885›Full record

ArticleMolecules (Basel, Switzerland)2022

The Improved Milk Quality and Enhanced Anti-Inflammatory Effect in Acetylserotonin-O-methyltransferase (

Hao Wu, Xudai Cui, Shengyu Guan, Guangdong Li, Yujun Yao, Haixin Wu, Jinlong Zhang, Xiaosheng Zhang, Tuan Yu, Yunxiang Li and 3 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Effects of SNPs inGenes · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Hao WuNational Engineering Laboratory for Animal Breeding, Key Laboratory of Animal Genetics and Breeding of the Ministry of Agricultural, Beijing Key Laboratory for Animal Genetic Improvement, College of Animal Science and Technology, China Agricultural University, Beijing 100193, China.ORCID 0000-0002-0336-0955
Xudai CuiQingdao Senmiao Industrial Co., Ltd., Qingdao 266101, China.
Shengyu GuanNational Engineering Laboratory for Animal Breeding, Key Laboratory of Animal Genetics and Breeding of the Ministry of Agricultural, Beijing Key Laboratory for Animal Genetic Improvement, College of Animal Science and Technology, China Agricultural University, Beijing 100193, China.
Guangdong LiNational Engineering Laboratory for Animal Breeding, Key Laboratory of Animal Genetics and Breeding of the Ministry of Agricultural, Beijing Key Laboratory for Animal Genetic Improvement, College of Animal Science and Technology, China Agricultural University, Beijing 100193, China.
Yujun YaoNational Engineering Laboratory for Animal Breeding, Key Laboratory of Animal Genetics and Breeding of the Ministry of Agricultural, Beijing Key Laboratory for Animal Genetic Improvement, College of Animal Science and Technology, China Agricultural University, Beijing 100193, China.
Haixin WuNational Engineering Laboratory for Animal Breeding, Key Laboratory of Animal Genetics and Breeding of the Ministry of Agricultural, Beijing Key Laboratory for Animal Genetic Improvement, College of Animal Science and Technology, China Agricultural University, Beijing 100193, China.
Jinlong ZhangTianjin Institute of Animal Husbandry and Veterinary, Tianjin 300192, China.
Xiaosheng ZhangTianjin Institute of Animal Husbandry and Veterinary, Tianjin 300192, China.
Tuan YuTianheng Animal Health and Product Quality Supervision Station, Qingdao 266200, China.
Yunxiang LiQingdao Senmiao Industrial Co., Ltd., Qingdao 266101, China.
Zhengxing LianNational Engineering Laboratory for Animal Breeding, Key Laboratory of Animal Genetics and Breeding of the Ministry of Agricultural, Beijing Key Laboratory for Animal Genetic Improvement, College of Animal Science and Technology, China Agricultural University, Beijing 100193, China.
Lu ZhangNational Engineering Laboratory for Animal Breeding, Key Laboratory of Animal Genetics and Breeding of the Ministry of Agricultural, Beijing Key Laboratory for Animal Genetic Improvement, College of Animal Science and Technology, China Agricultural University, Beijing 100193, China.
Guoshi LiuNational Engineering Laboratory for Animal Breeding, Key Laboratory of Animal Genetics and Breeding of the Ministry of Agricultural, Beijing Key Laboratory for Animal Genetic Improvement, College of Animal Science and Technology, China Agricultural University, Beijing 100193, China.ORCID 0000-0002-5688-3645
China Agricultural University · CNAnimal Science Research Institute · CN

Funding

Ministry of Agriculture and Rural Affairs 2016ZX08008003Ministry of Agriculture and Rural Affairs 2018ZX0800801B
6 · The paper itself

Abstract

backgroundTransgenic animal production is an important means of livestock breeding and can be used to model pharmaceutical applications.

methodsIn this study, to explore the biological activity of endogenously produced melatonin, Acetylserotonin-O-methyltransferase (

resultsThese transgenic goats have the same normal phenotype as the wild-type goats (WT). However, the melatonin levels in their blood and milk were significantly increased (

conclusionsThe increased melatonin production due to

Indexed as

Acetylserotonin O-MethyltransferaseAnimals, Genetically ModifiedGoatsMelatoninMilkAnimalsAnti-Inflammatory AgentsCytokinesFemaleGastrointestinal MicrobiomeAcetylserotonin O-MethyltransferaseAnti-Inflammatory AgentsCytokinesMelatoninacetylserotonin-O-methyltransferase (ASMT)arachidonic acidcytokinesgoatintestinal microbiotamelatoninmilk quality

Identifiers

PMID35056885
PMCPMC8778916
OpenAlexW4205175426

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.