Evidence map›Paper›PMID 35056852›Full record

ArticleMolecules (Basel, Switzerland)2022

Microwave-Assisted Desulfation of the Hemolytic Saponins Extracted from

Philippe Savarino, Emmanuel Colson, Guillaume Caulier, Igor Eeckhaut, Patrick Flammang, Pascal Gerbaux

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.7field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Impact of the Hydrolysis and Methanolysis of BidesmosidicMolecules (Basel, Switzerland) · 2022
    Article
  8. Review
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 2 countries.

Philippe SavarinoOrganic Synthesis and Mass Spectrometry Laboratory (S²MOs), University of Mons, 23 Place du Parc, 7000 Mons, Belgium.ORCID 0000-0002-2590-196X
Emmanuel ColsonOrganic Synthesis and Mass Spectrometry Laboratory (S²MOs), University of Mons, 23 Place du Parc, 7000 Mons, Belgium.
Guillaume CaulierBiology of Marine Organisms and Biomimetics Unit (BOMB), Research Institute for Biosciences, University of Mons, 23 Place du Parc, 7000 Mons, Belgium.ORCID 0000-0001-7414-1226
Igor EeckhautBiology of Marine Organisms and Biomimetics Unit (BOMB), Research Institute for Biosciences, University of Mons, 23 Place du Parc, 7000 Mons, Belgium.
Patrick FlammangBiology of Marine Organisms and Biomimetics Unit (BOMB), Research Institute for Biosciences, University of Mons, 23 Place du Parc, 7000 Mons, Belgium.ORCID 0000-0001-9938-1154
Pascal GerbauxOrganic Synthesis and Mass Spectrometry Laboratory (S²MOs), University of Mons, 23 Place du Parc, 7000 Mons, Belgium.ORCID 0000-0001-5114-4352
University of Mons · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Saponins are plant and marine animal specific metabolites that are commonly considered as molecular vectors for chemical defenses against unicellular and pluricellular organisms. Their toxicity is attributed to their membranolytic properties. Modifying the molecular structures of saponins by quantitative and selective chemical reactions is increasingly considered to tune the biological properties of these molecules (i) to prepare congeners with specific activities for biomedical applications and (ii) to afford experimental data related to their structure-activity relationship. In the present study, we focused on the sulfated saponins contained in the viscera of

Indexed as

AlkaliesAnimalsCattleChromatography, LiquidHemolysisHemolytic AgentsHolothuriaHydrolysisIndian OceanMicrowavesSaponinsSpectrometry, Mass, Matrix-Assisted Laser Desorption-IonizationStructure-Activity RelationshipSulfatesTandem Mass SpectrometryVisceraAlkaliesHemolytic AgentsSaponinsSulfatesdesulfationhemolytic activitymass spectrometrymicrowave activationsaponinssea cucumberstriterpene glycosides

Identifiers

PMID35056852
PMCPMC8780253
OpenAlexW4205963246

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.