Evidence map›Paper›PMID 35056685›Full record

ReviewMolecules (Basel, Switzerland)2022

Alternative Extraction and Downstream Purification Processes for Anthocyanins.

Ana N Nunes, Alexandra Borges, Ana A Matias, Maria Rosário Bronze, Joana Oliveira

Abstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ana N NunesiBET, Instituto de Biologia Experimental e Tecnológica, 2780-901 Oeiras, Portugal.ORCID 0000-0002-8842-1509
Alexandra BorgesLaboratório Associado para a Química Verde-REQUIMTE, Departamento de Química e Bioquímica, Faculdade de Ciências da Universidade do Porto, Rua do Campo Alegre S/N, 4169-007 Porto, Portugal.
Ana A MatiasiBET, Instituto de Biologia Experimental e Tecnológica, 2780-901 Oeiras, Portugal.
Maria Rosário BronzeiBET, Instituto de Biologia Experimental e Tecnológica, 2780-901 Oeiras, Portugal.ORCID 0000-0001-5016-4634
Joana OliveiraLaboratório Associado para a Química Verde-REQUIMTE, Departamento de Química e Bioquímica, Faculdade de Ciências da Universidade do Porto, Rua do Campo Alegre S/N, 4169-007 Porto, Portugal.ORCID 0000-0002-9996-1463

Funding

European Regional Development Fund NORTE-01-0145-FEDER-000041Fundação para a Ciência e Tecnologia IF/00225/2015Fundação para a Ciência e Tecnologia UIDB/50006/2020 and UIDP/50006/2020
6 · The paper itself

Abstract

Anthocyanins are natural pigments displaying different attractive colors ranging from red, violet, to blue. These pigments present health benefits that increased their use in food, nutraceuticals, and the cosmetic industry. However, anthocyanins are mainly extracted through conventional methods that are time-consuming and involve the use of organic solvents. Moreover, the chemical diversity of the obtained complex extracts make the downstream purification step challenging. Therefore, the growing demand of these high-value pigments has stimulated the interest in designing new, safe, cost-effective, and tunable strategies for their extraction and purification. The current review focuses on the potential application of compressed fluid-based (such as subcritical and supercritical fluid extraction and pressurized liquid extraction) and deep eutectic solvents-based extraction methods for the recovery of anthocyanins. In addition, an updated review of the application of counter-current chromatography for anthocyanins purification is provided as a faster and cost-effective alternative to preparative-scale HPLC.

Indexed as

AnthocyaninsSolventsChemical FractionationChromatography, High Pressure LiquidChromatography, Supercritical FluidCountercurrent DistributionLiquid-Liquid ExtractionPlant ExtractsAnthocyaninsPlant ExtractsSolventsalternative solventsanthocyaninscounter-current chromatographydownstream processes

Identifiers

PMID35056685
PMCPMC8779312

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.