Evidence map›Paper›PMID 35056608›Full record

ArticleMicroorganisms2022

Plethora of Resistance Genes in Carbapenem-Resistant Gram-Negative Bacteria in Greece: No End to a Continuous Genetic Evolution.

Katerina Tsilipounidaki, Zoi Athanasakopoulou, Elke Müller, Sindy Burgold-Voigt, Zoi Florou, Sascha D Braun, Stefan Monecke, Nikolaos K Gatselis, Kalliopi Zachou, Aggelos Stefos and 7 more

Open access · goldAbstract read
In one paragraph

Article in Microorganisms, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.1field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 2 institutions in 2 countries.

Katerina TsilipounidakiFaculty of Medicine, University of Thessaly, 41500 Larissa, Greece.
Zoi AthanasakopoulouFaculty of Veterinary Science, University of Thessaly, 43100 Karditsa, Greece.
Elke MüllerLeibniz Institute of Photonic Technology (IPHT), 07745 Jena, Germany.
Sindy Burgold-VoigtLeibniz Institute of Photonic Technology (IPHT), 07745 Jena, Germany.
Zoi FlorouFaculty of Medicine, University of Thessaly, 41500 Larissa, Greece.
Sascha D BraunLeibniz Institute of Photonic Technology (IPHT), 07745 Jena, Germany.
Stefan MoneckeLeibniz Institute of Photonic Technology (IPHT), 07745 Jena, Germany.
Nikolaos K GatselisFaculty of Medicine, University of Thessaly, 41500 Larissa, Greece.
Kalliopi ZachouFaculty of Medicine, University of Thessaly, 41500 Larissa, Greece.
Aggelos StefosFaculty of Medicine, University of Thessaly, 41500 Larissa, Greece.
Ilias TsagalasFaculty of Medicine, University of Thessaly, 41500 Larissa, Greece.
Marina SofiaFaculty of Veterinary Science, University of Thessaly, 43100 Karditsa, Greece.
Vassiliki SpyrouFaculty of Animal Science, University of Thessaly, 41110 Larissa, Greece.
Charalambos BillinisFaculty of Veterinary Science, University of Thessaly, 43100 Karditsa, Greece.ORCID 0000-0002-2209-9772
George N DalekosFaculty of Medicine, University of Thessaly, 41500 Larissa, Greece.
Ralf EhrichtLeibniz Institute of Photonic Technology (IPHT), 07745 Jena, Germany.ORCID 0000-0002-6612-0043
Efthymia PetinakiFaculty of Medicine, University of Thessaly, 41500 Larissa, Greece.
University of Thessaly · GRLeibniz Institute of Photonic Technology · DE

Funding

European Union, the Greek General Secretariat for Research and Innovation, Ministry of Development & Investments, the German Federal Ministry of Education and Research T2DGE-0944 (Greek side), 01EI1701 (German side)
6 · The paper itself

Abstract

Carbapenem-resistant Gram-negative bacteria are a public health threat that requires urgent action. The fact that these pathogens commonly also harbor resistance mechanisms for several other antimicrobial classes further reduces patient treatment options. The present study aimed to provide information regarding the multidrug resistance genetic background of carbapenem-resistant Gram-negative bacteria in Central Greece. Strains from a tertiary care hospital, collected during routine practice, were characterized using a DNA microarray-based assay. Various different resistance determinants for carbapenems, other beta-lactams, aminoglycosides, quinolones, trimethoprim, sulfonamides and macrolides were detected among isolates of the same sequence type. Eighteen different multidrug resistance genomic profiles were identified among the twenty-four

Indexed as

Acinetobacter baumanniiantimicrobial resistance genescarbapenem resistanceGreeceKlebsiella pneumoniaePseudomonas aeruginosa

Identifiers

PMID35056608
PMCPMC8781379
OpenAlexW4205194211

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.