Evidence map›Paper›PMID 35056592›Full record

ArticleMicroorganisms2022

SARS-CoV-2 Evolution and Spike-Specific CD4+ T-Cell Response in Persistent COVID-19 with Severe HIV Immune Suppression.

Hortensia Álvarez, Ezequiel Ruiz-Mateos, Pedro Miguel Juiz-González, Joana Vitallé, Irene Viéitez, María Del Carmen Vázquez-Friol, Isabel Torres-Beceiro, Alberto Pérez-Gómez, Pilar Gallego-García, Nuria Estévez-Gómez and 4 more

Open access · goldAbstract readCase Reports
In one paragraph

Article in Microorganisms, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Article
  3. The immune response to SARS-CoV-2 in people with HIV.Cellular & molecular immunology · 2024
    Review
  4. Review
  5. Trends in the Epidemiology ofJournal of fungi (Basel, Switzerland) · 2023
    Review
  6. Article
  7. Antigenic evolution of SARS-CoV-2 in immunocompromised hosts.Evolution, medicine, and public health · 2023
    Article
  8. Review
  9. Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 5 institutions in 1 country.

Hortensia ÁlvarezInfectious Diseases Unit, Department of Internal Medicine, University Hospital of Ferrol, SERGAS, 15405 Ferrol, Spain.ORCID 0000-0002-5002-1737
Ezequiel Ruiz-MateosClinic Unit of Infectious Diseases, Microbiology and Preventive Medicine, Institute of Biomedicine of Seville, IBiS, Virgen del Rocío University Hospital/CSIC/University of Seville, 41013 Seville, Spain.ORCID 0000-0001-6747-7813
Pedro Miguel Juiz-GonzálezMicrobiology Department, University Hospital of Ferrol, SERGAS, 15405 Ferrol, Spain.
Joana VitalléClinic Unit of Infectious Diseases, Microbiology and Preventive Medicine, Institute of Biomedicine of Seville, IBiS, Virgen del Rocío University Hospital/CSIC/University of Seville, 41013 Seville, Spain.ORCID 0000-0002-5292-1851
Irene ViéitezGroup of Virology and Pathogenesis, Galicia Sur Health Research Institute (IIS Galicia Sur), Complexo Hospitalario Universitario de Vigo, SERGAS-UVIGO, 36213 Vigo, Spain.ORCID 0000-0001-9241-0207
María Del Carmen Vázquez-FriolInternal Medicine Department, University Hospital of Ferrol, SERGAS, 15405 Ferrol, Spain.
Isabel Torres-BeceiroMicrobiology Department, University Hospital of Ferrol, SERGAS, 15405 Ferrol, Spain.
Alberto Pérez-GómezClinic Unit of Infectious Diseases, Microbiology and Preventive Medicine, Institute of Biomedicine of Seville, IBiS, Virgen del Rocío University Hospital/CSIC/University of Seville, 41013 Seville, Spain.ORCID 0000-0002-3644-2914
Pilar Gallego-GarcíaCINBIO, Universidade de Vigo, 36310 Vigo, Spain.ORCID 0000-0001-8531-9851
Nuria Estévez-GómezCINBIO, Universidade de Vigo, 36310 Vigo, Spain.ORCID 0000-0002-7281-3137
Loretta De ChiaraCINBIO, Universidade de Vigo, 36310 Vigo, Spain.ORCID 0000-0001-7700-6417
Eva PovedaGroup of Virology and Pathogenesis, Galicia Sur Health Research Institute (IIS Galicia Sur), Complexo Hospitalario Universitario de Vigo, SERGAS-UVIGO, 36213 Vigo, Spain.ORCID 0000-0003-4835-9875
David PosadaCINBIO, Universidade de Vigo, 36310 Vigo, Spain.ORCID 0000-0003-1407-3406
Josep M LlibreInfectious Diseases and "Fight AIDS and Infectious Diseases" Foundation, University Hospital Germans Trias i Pujol, 08916 Badalona, Spain.ORCID 0000-0002-7158-6753
Galicia Sur Biomedical Foundation · ESServicio Gallego de Salud · ESInstituto de Biomedicina de Sevilla · ESUniversity Hospital Complex Of Vigo · ESFundació Lluita contra les Infeccions · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Intra-host evolution of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been reported in cases with persistent coronavirus disease 2019 (COVID-19). In this study, we describe a severely immunosuppressed individual with HIV-1/SARS-CoV-2 coinfection with a long-term course of SARS-CoV-2 infection. A 28-year-old man was diagnosed with HIV-1 infection (CD4+ count: 3 cells/µL nd 563000 HIV-1 RNA copies/mL) and simultaneous

Indexed as

CD4+ T cell responseHIVSARS-CoV-2

Identifiers

PMID35056592
PMCPMC8780218
OpenAlexW4206072106

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.