Evidence map›Paper›PMID 35056336›Full record

ArticleMedicina (Kaunas, Lithuania)2021

Orthostatic Symptoms and Reductions in Cerebral Blood Flow in Long-Haul COVID-19 Patients: Similarities with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome.

C Linda M C van Campen, Peter C Rowe, Frans C Visser

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Medicina (Kaunas, Lithuania), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05664711 (Effect of Stellate Ganglion Block on ME/CFS Symptoms and Metabolites), which is not on this map. Cited by 52 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
52citing papers in PubMed, 2 pooled it
8.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05664711 phase1completednot on this mapstarted 2023, after this paper: background citation

Effect of Stellate Ganglion Block on ME/CFS Symptoms and Metabolites

TypeinterventionalSponsorNeuroversion, Inc.Ran2023 to 2024Enrolled10ConditionsEncephalomyelitis, Myalgic, Chronic Fatigue Syndrome, Chronic Fatigue Disorder, Chronic Fatigue and Immune Dysfunction SyndromeArmsBupivacaine Injection
3 · Its place in the literature

Who cites it

52 citing papers in PubMed, 2 syntheses or guidelines pooled it, 73 citations in OpenAlex.

  1. Recent research in myalgic encephalomyelitis/chronic fatigue syndrome: an evidence map.Health technology assessment (Winchester, England) · 2025
    Pooled it
  2. Faintly tired: a systematic review of fatigue in patients with orthostatic syncope.Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2022
    Pooled it
  3. Article
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  11. Cerebral Blood Flow in Orthostatic Intolerance.Journal of the American Heart Association · 2025
    Review
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  16. Article
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  19. Illness presentation and quality of life in myalgic encephalomyelitis/chronic fatigue syndrome and post COVID-19 condition: a pilot Australian cross-sectional study.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2024
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

C Linda M C van CampenStichting CardioZorg, Planetenweg 5, 2132 HN Hoofddorp, The Netherlands.ORCID 0000-0002-2570-0914
Peter C RoweDepartment of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.ORCID 0000-0002-3586-2677
Frans C VisserStichting CardioZorg, Planetenweg 5, 2132 HN Hoofddorp, The Netherlands.
Johns Hopkins University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

COVID-19Fatigue Syndrome, ChronicBlood PressureCerebrovascular CirculationHumansPost-Acute COVID-19 SyndromeSARS-CoV-2cerebral blood flow (CBF)chronic fatigue syndrome (CFS)long-haul COVID-19myalgic encephalomyelitis (ME)orthostatic intolerancepostural orthostatic tachycardia syndrome (POTS)tilt testing

Identifiers

PMID35056336
PMCPMC8778312
OpenAlexW4200627918

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.