Evidence map›Paper›PMID 35056208›Full record

ArticleMicromachines2021

Development of Silk Fibroin Scaffolds by Using Indirect 3D-Bioprinting Technology.

Yeong-Jin Choi, Dong-Woo Cho, Hyungseok Lee

Abstract read
In one paragraph

Article in Micromachines, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Three-dimensional-printed shape-memory composite scaffold for meniscus repair.The Journal of international medical research · 2026
    Article
  2. Review
  3. Review
  4. An All-In-One Transient Theranostic Platform for Intelligent Management of Hemorrhage.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2023
    Article
  5. Article
  6. Review
  7. Review
  8. Article
  9. Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Yeong-Jin ChoiDepartment of Advanced Biomaterials Research, Korea Institute of Materials Science (KIMS), 797, Changwon-daero, Seongsan-gu, Changwon-si 51508, Korea.ORCID 0000-0002-5211-8436
Dong-Woo ChoDepartment of Mechanical Engineering, Pohang University of Science and Technology (POSTECH), Pohang 37673, Korea.
Hyungseok LeeDepartment of Mechanical and Biomedical Engineering, Kangwon National University (KNU), 1 Gangwondaehakgil, Chuncheon-si 24341, Korea.

Funding

2020 Research Grant from Kangwon National University 2020 Research Grant from Kangwon National UniversityFundamental Research Program of the Korea Institute of Material Science PNK7490Ministry of Trade, Industry & Energy (MOTIE, Korea) 20015148National Research Foundation of Korea (NRF) grants funded by the Korea government (MSIT) 2020R1A4A1019475National Research Foundation of Korea (NRF) grants funded by the Korea government (MSIT) 2020R1C1C1011147
6 · The paper itself

Abstract

Due to the excellent biocompatibility of natural polymers, a variety of natural polymers have been widely used as biomaterials for manufacturing tissue engineered scaffolds. Despite the excellent biological activity of natural polymers, there have been obstacles in using them on their own to prepare 3D scaffolds with sufficient mechanical strength. Although multiple 3D-bioprinting technologies have recently emerged as effective manufacturing tools for scaffold preparation, scaffold preparation using only natural polymers with tunable mechanical properties is still difficult. Herein, we introduce novel scaffold fabrication methods using the natural polymer silk fibroin via indirect 3D-bioprinting technology. The developed silk fibroin scaffolds showed biocompatibility and tunable mechanical strength by changing the concentration of the silk fibroin. Furthermore, controlling the flexibility of the silk fibroin scaffolds was made possible by changing the solvent for the silk fibroin solution used to fabricate the scaffold. Consequently, silk fibroin scaffolds fabricated via our method can be considered for various applications in the bioengineering of either soft or musculoskeletal tissues.

Indexed as

3D-bioprintingindirectnatural polymerscaffoldsilk fibrointunable mechanical property

Identifiers

PMID35056208
PMCPMC8779165

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.