Evidence map›Paper›PMID 35056108›Full record

ArticlePharmaceuticals (Basel, Switzerland)2021

Discovery of Small Molecules as Membrane-Bound Catechol-

Pedro Cruz-Vicente, Ana M Gonçalves, Octávio Ferreira, João A Queiroz, Samuel Silvestre, Luís A Passarinha, Eugenia Gallardo

Open access · goldAbstract read
In one paragraph

Article in Pharmaceuticals (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.1field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Pedro Cruz-VicenteCICS-UBI, Health Sciences Research Centre, Universidade da Beira Interior, 6201-001 Covilha, Portugal.ORCID 0000-0001-8552-6180
Ana M GonçalvesCICS-UBI, Health Sciences Research Centre, Universidade da Beira Interior, 6201-001 Covilha, Portugal.
Octávio FerreiraCICS-UBI, Health Sciences Research Centre, Universidade da Beira Interior, 6201-001 Covilha, Portugal.
João A QueirozCICS-UBI, Health Sciences Research Centre, Universidade da Beira Interior, 6201-001 Covilha, Portugal.ORCID 0000-0002-3096-8325
Samuel SilvestreCICS-UBI, Health Sciences Research Centre, Universidade da Beira Interior, 6201-001 Covilha, Portugal.ORCID 0000-0003-4297-5108
Luís A PassarinhaCICS-UBI, Health Sciences Research Centre, Universidade da Beira Interior, 6201-001 Covilha, Portugal.ORCID 0000-0001-6910-7576
Eugenia GallardoCICS-UBI, Health Sciences Research Centre, Universidade da Beira Interior, 6201-001 Covilha, Portugal.ORCID 0000-0002-1802-8998
University of Beira Interior · PT

Funding

European Regional Development Fund Project Centro-01-0145-FEDER-000019-C4-Centro de Competências em Cloud ComputingFundação para a Ciência e Tecnologia project LA/P/0140/2020Fundação para a Ciência e Tecnologia SFRH/BD/141900/2018Fundação para a Ciência e Tecnologia SFRH/BD/147519 /2019Fundação para a Ciência e Tecnologia UIDB/00709/2020Fundação para a Ciência e Tecnologia UIDB/04378/2020Fundação para a Ciência e Tecnologia UIDP/00709/2020Fundação para a Ciência e Tecnologia UIDP/04378/2020
6 · The paper itself

Abstract

A pharmacophore-based virtual screening methodology was used to discover new catechol-

Indexed as

bioinformaticscatechol-O-methyltransferasecytotoxicityinhibitorsmolecular dockingParkinson’s diseasepharmacophore modeling

Identifiers

PMID35056108
PMCPMC8780549
OpenAlexW4205809082

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.