Evidence map›Paper›PMID 35056071›Full record

ReviewPharmaceuticals (Basel, Switzerland)2021

Expanding Theranostic Radiopharmaceuticals for Tumor Diagnosis and Therapy.

Cristina Barca, Christoph M Griessinger, Andreas Faust, Dominic Depke, Markus Essler, Albert D Windhorst, Nick Devoogdt, Kevin M Brindle, Michael Schäfers, Bastian Zinnhardt and 1 more

Open access · goldAbstract readReview
In one paragraph

Review in Pharmaceuticals (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
5.8field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 64 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Quantitative Comparison of SPECT and PET Performance for Clinical Theranostic Applications.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2026
    Article
  6. DFT calculation of AcScientific reports · 2026
    Article
  7. Review
  8. Review
  9. Review
  10. Review
  11. Article
  12. Review
  13. Review
  14. Article
  15. Exploring innovative strides in radiolabeled nanoparticle progress for multimodality cancer imaging and theranostic applications.Cancer imaging : the official publication of the International Cancer Imaging Society · 2024
    Review
  16. Article
  17. Article
  18. Complexation of 3p-Heliyon · 2024
    Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 5 countries.

Cristina BarcaEuropean Institute for Molecular Imaging, University of Münster, D-48149 Münster, Germany.ORCID 0000-0001-8034-2948
Christoph M GriessingerRoche Innovation Center, Early Clinical Development Oncology, Roche Pharmaceutical Research and Early Development, CH-4070 Basel, Switzerland.
Andreas FaustEuropean Institute for Molecular Imaging, University of Münster, D-48149 Münster, Germany.
Dominic DepkeEuropean Institute for Molecular Imaging, University of Münster, D-48149 Münster, Germany.
Markus EsslerDepartment of Nuclear Medicine, University Hospital Bonn, D-53127 Bonn, Germany.
Albert D WindhorstDepartment Radiology & Nuclear Medicine, Amsterdam UMC, Vrije Universiteit, De Boelelaan 1117, 1081HV Amsterdam, The Netherlands.
Nick DevoogdtIn Vivo Cellular and Molecular Imaging Laboratory, Vrije Universiteit Brussel, B-1090 Brussel, Belgium.ORCID 0000-0001-9220-4833
Kevin M BrindleCancer Research UK Cambridge Institute, University of Cambridge, Cambridge CB2 ORE, UK.ORCID 0000-0003-3883-6287
Michael SchäfersEuropean Institute for Molecular Imaging, University of Münster, D-48149 Münster, Germany.
Bastian ZinnhardtEuropean Institute for Molecular Imaging, University of Münster, D-48149 Münster, Germany.ORCID 0000-0002-8274-9108
Andreas H JacobsEuropean Institute for Molecular Imaging, University of Münster, D-48149 Münster, Germany.
University of Münster · DERoche (Switzerland) · CHAmsterdam University Medical Centers · NLUniversity Hospital Bonn · DEUniversity of Cambridge · GBVrije Universiteit Brussel · BE

Funding

Cancer Research UK 28289
6 · The paper itself

Abstract

Radioligand theranostics (RT) in oncology use cancer-type specific biomarkers and molecular imaging (MI), including positron emission tomography (PET), single-photon emission computed tomography (SPECT) and planar scintigraphy, for patient diagnosis, therapy, and personalized management. While the definition of theranostics was initially restricted to a single compound allowing visualization and therapy simultaneously, the concept has been widened with the development of theranostic pairs and the combination of nuclear medicine with different types of cancer therapies. Here, we review the clinical applications of different theranostic radiopharmaceuticals in managing different tumor types (differentiated thyroid, neuroendocrine prostate, and breast cancer) that support the combination of innovative oncological therapies such as gene and cell-based therapies with RT.

Indexed as

cell-based therapygene therapymolecular imagingpositron emission tomographyradiopharmaceuticalstheranosticstumor

Identifiers

PMID35056071
PMCPMC8780589
OpenAlexW4200389224

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.