Evidence map›Paper›PMID 35056023›Full record

ReviewPathogens (Basel, Switzerland)2022

Vaccines for Mycoplasma Diseases of Small Ruminants: A Neglected Area of Research.

Katarzyna Dudek, Umit Sevimli, Sergio Migliore, Amirreza Jafarizadeh, Guido R Loria, Robin A J Nicholas

Open access · goldAbstract readReview
In one paragraph

Review in Pathogens (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. First Description ofMicroorganisms · 2024
    Article
  6. Article
  7. Isolation and Characterization ofLife (Basel, Switzerland) · 2024
    Article
  8. Vaccines · 2024
    Review
  9. Article
  10. Review
  11. Pathogens (Basel, Switzerland) · 2022
    Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 5 countries.

Katarzyna DudekDepartment of Cattle and Sheep Diseases, National Veterinary Research Institute, 57 Partyzantów Avenue, 24100 Pulawy, Poland.ORCID 0000-0002-3271-3748
Umit SevimliPendik Veterinary Control Institute, OIE Reference Laboratory for CCPP, Pendik, Istanbul 34890, Turkey.
Sergio MiglioreArea Diagnostica Specialistica, OIE Reference Laboratory for Contagious Agalactia, Istituto Zooprofilattico Sperimentale della Sicilia, Via G. Marinuzzi 3, 90129 Palermo, Italy.ORCID 0000-0002-6685-7109
Amirreza JafarizadehDepartment of Microbiology, Faculty of Veterinary Sciences, Science and Research Branch, Islamic Azad University, Tehran 477893855, Iran.ORCID 0000-0002-3908-8025
Guido R LoriaArea Diagnostica Specialistica, OIE Reference Laboratory for Contagious Agalactia, Istituto Zooprofilattico Sperimentale della Sicilia, Via G. Marinuzzi 3, 90129 Palermo, Italy.
Robin A J NicholasThe Oaks, Nutshell Lane, Farnham, Surrey GU9 0HG, UK.
Istituto Zooprofilattico Sperimentale Della Sicilia · ITGedik University · TRIslamic Azad University, Science and Research Branch · IRNational Veterinary Research Institute · PLOaks Hospital · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mycoplasmas cause some of the most economically important diseases of sheep and goats, including diseases listed by the World Organisation for Animal Health (OIE) such as contagious caprine pleuropneumonia (CCPP) and contagious agalactia (CA). Other important mycoplasma diseases include chronic respiratory and arthritic syndrome (CRAS) and atypical pneumonia, both present on all continents where small ruminants are farmed. Unfortunately, owing to a lack of investment, most commercial vaccines for these diseases are of poor quality, being mostly composed of killed bacteriocins of dubious or unknown efficacy. Several Mediterranean laboratories produce autogenous vaccines, but these can only be used on farms where outbreaks have been officially declared, and consequently have limited impact on disease nationally. Effective live vaccines are available, but their use is often restricted because of safety concerns. With the necessary safeguards in place, we argue for their greater use. This review examines reported vaccines for mycoplasma diseases of small ruminants and attempts to identify new candidate antigens that may enable the development of improved products. Vaccines for CCPP are covered elsewhere.

Indexed as

mycoplasmasmall ruminantsvaccines

Identifiers

PMID35056023
PMCPMC8781016
OpenAlexW4206197620

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.