Evidence map›Paper›PMID 35056021›Full record

ArticlePathogens (Basel, Switzerland)2022

Amphotericin B Polymer Nanoparticles Show Efficacy against

Abdulghani Alakkad, Paul Stapleton, Corinna Schlosser, Sudaxshina Murdan, Uchechukwu Odunze, Andreas Schatzlein, Ijeoma F Uchegbu

Open access · goldAbstract read
In one paragraph

Article in Pathogens (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 19 citations in OpenAlex.

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  11. Inhibition ofPharmaceutics · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Abdulghani AlakkadUCL School of Pharmacy, University College London (UCL), 29-39 Brunswick Square, London WC1N 1AX, UK.
Paul StapletonUCL School of Pharmacy, University College London (UCL), 29-39 Brunswick Square, London WC1N 1AX, UK.
Corinna SchlosserUCL School of Pharmacy, University College London (UCL), 29-39 Brunswick Square, London WC1N 1AX, UK.
Sudaxshina MurdanUCL School of Pharmacy, University College London (UCL), 29-39 Brunswick Square, London WC1N 1AX, UK.ORCID 0000-0003-0834-7757
Uchechukwu OdunzeUCL School of Pharmacy, University College London (UCL), 29-39 Brunswick Square, London WC1N 1AX, UK.
Andreas SchatzleinUCL School of Pharmacy, University College London (UCL), 29-39 Brunswick Square, London WC1N 1AX, UK.ORCID 0000-0003-3907-6603
Ijeoma F UchegbuUCL School of Pharmacy, University College London (UCL), 29-39 Brunswick Square, London WC1N 1AX, UK.ORCID 0000-0001-9586-6867
University College London · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeChronic infections of

methodsAmB was encapsulated in the Molecular Envelope Technology (MET, N-palmitoyl-N-monomethyl-N,N-dimethyl-N,N,N-trimethyl-6-O-glycolchitosan) nanoparticles and tested against

resultsMET-AmB formulations demonstrated superior activity towards

conclusionsThese biofilm activity findings raise the possibility that MET-loaded nanoparticles may be used to tackle

Indexed as

biofilmC. albicansCandidaC. glabrataGCPQnanoparticlesN-palmitoyl-N-monomethyl-N,N-diemthyl-N,N,N-trimethyl-6-O-glycolchitosan

Identifiers

PMID35056021
PMCPMC8781556
OpenAlexW4205435461

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.