Evidence map›Paper›PMID 35056008›Full record

ReviewPathogens (Basel, Switzerland)2022

Enteroviral Infections in the First Three Months of Life.

Marcello Sandoni, Lidia Ciardo, Caterina Tamburini, Alessandra Boncompagni, Cecilia Rossi, Isotta Guidotti, Elisabetta Garetti, Licia Lugli, Lorenzo Iughetti, Alberto Berardi

Open access · goldAbstract readReview
In one paragraph

Review in Pathogens (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
4.8field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 30 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. [Neonatal myocarditis due to Coxsackie: case report and literature review].Revista medica del Instituto Mexicano del Seguro Social · 2024
    Review
  10. Article
  11. Article
  12. Article
  13. Increased reports of severe myocarditis associated with enterovirus infection in neonates, United Kingdom, 27 June 2022 to 26 April 2023.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2023
    Article
  14. Article
  15. Severe and fatal neonatal infections linked to a new variant of echovirus 11, France, July 2022 to April 2023.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2023
    Article
  16. Article
  17. Vertical Transmission of Coxsackievirus A6 with Severe Congenital Pneumonia/Sepsis.International journal of environmental research and public health · 2023
    Article
  18. Review
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Marcello SandoniPediatric Post-Graduate School, University of Modena and Reggio Emilia, 41125 Modena, Italy.
Lidia CiardoPediatric Post-Graduate School, University of Modena and Reggio Emilia, 41125 Modena, Italy.
Caterina TamburiniPediatric Post-Graduate School, University of Modena and Reggio Emilia, 41125 Modena, Italy.
Alessandra BoncompagniNeonatal Intensive Care Unit, Women's and Children's Health Department, Azienda Ospedaliera, University of Modena and Reggio Emilia, 41125 Modena, Italy.
Cecilia RossiNeonatal Intensive Care Unit, Women's and Children's Health Department, Azienda Ospedaliera, University of Modena and Reggio Emilia, 41125 Modena, Italy.
Isotta GuidottiNeonatal Intensive Care Unit, Women's and Children's Health Department, Azienda Ospedaliera, University of Modena and Reggio Emilia, 41125 Modena, Italy.
Elisabetta GarettiNeonatal Intensive Care Unit, Women's and Children's Health Department, Azienda Ospedaliera, University of Modena and Reggio Emilia, 41125 Modena, Italy.
Licia LugliNeonatal Intensive Care Unit, Women's and Children's Health Department, Azienda Ospedaliera, University of Modena and Reggio Emilia, 41125 Modena, Italy.
Lorenzo IughettiPediatric Post-Graduate School, University of Modena and Reggio Emilia, 41125 Modena, Italy.
Alberto BerardiNeonatal Intensive Care Unit, Women's and Children's Health Department, Azienda Ospedaliera, University of Modena and Reggio Emilia, 41125 Modena, Italy.ORCID 0000-0002-3534-7499
University of Modena and Reggio Emilia · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Enteroviruses (EVs) are an important source of infection in the paediatric age, with most cases concerning the neonatal age and early infancy. Molecular epidemiology is crucial to understand the circulation of main serotypes in a specific area and period due to their extreme epidemiological variability. The diagnosis of EVs infection currently relies on the detection of EVs RNA in biological samples (usually cerebrospinal fluid and plasma, but also throat swabs and feces) through a polymerase chain reaction assay. Although EVs infections usually have a benign course, they sometimes become life threatening, especially when symptoms develop in the first few days of life. Mortality is primarily associated with myocarditis, acute hepatitis, and multi-organ failure. Neurodevelopmental sequelae have been reported following severe infections with central nervous system involvement. Unfortunately, at present, the treatment of EVs infections is mainly supportive. The use of specific antiviral agents in severe neonatal infections has been reported in single cases or studies including few neonates. Therefore, further studies are needed to confirm the efficacy of these drugs in clinical practice.

Indexed as

enterovirusinfantinfectionneonatetreatment

Identifiers

PMID35056008
PMCPMC8782040
OpenAlexW4205427314

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.