Evidence map›Paper›PMID 35055627›Full record

ArticleInternational journal of environmental research and public health2022

Variation in Cause-Specific Mortality Rates in Italy during the First Wave of the COVID-19 Pandemic: A Study Based on Nationwide Data.

Enrico Grande, Ugo Fedeli, Marilena Pappagallo, Roberta Crialesi, Stefano Marchetti, Giada Minelli, Ivano Iavarone, Luisa Frova, Graziano Onder, Francesco Grippo

Abstract read
In one paragraph

Article in International journal of environmental research and public health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 1 synthesis or guideline pooled it.

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  20. The impact of the SARS-CoV-2 pandemic on cause-specific mortality patterns: a systematic literature review.Zeitschrift fur Gesundheitswissenschaften = Journal of public health · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Enrico GrandeIntegrated System for Health, Social Assistance and Welfare, Italian National Institute of Statistics, 00198 Rome, Italy.ORCID 0000-0003-3382-2708
Ugo FedeliEpidemiological Department, Azienda Zero, Veneto Region, 35132 Padova, Italy.ORCID 0000-0002-9939-3398
Marilena PappagalloIntegrated System for Health, Social Assistance and Welfare, Italian National Institute of Statistics, 00198 Rome, Italy.
Roberta CrialesiIntegrated System for Health, Social Assistance and Welfare, Italian National Institute of Statistics, 00198 Rome, Italy.
Stefano MarchettiIntegrated System for Health, Social Assistance and Welfare, Italian National Institute of Statistics, 00198 Rome, Italy.
Giada MinelliStatistical Service, Istituto Superiore di Sanità, 00161 Rome, Italy.ORCID 0000-0002-2752-9989
Ivano IavaroneDepartment of Environment and Health, Istituto Superiore di Sanità, 00161 Rome, Italy.ORCID 0000-0001-5856-9484
Luisa FrovaIntegrated System for Health, Social Assistance and Welfare, Italian National Institute of Statistics, 00198 Rome, Italy.ORCID 0000-0002-4594-1125
Graziano OnderDepartment of Cardiovascular, Endocrine-Metabolic Diseases and Ageing, Istituto Superiore di Sanità, 00161 Rome, Italy.
Francesco GrippoIntegrated System for Health, Social Assistance and Welfare, Italian National Institute of Statistics, 00198 Rome, Italy.ORCID 0000-0001-5471-8964

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Italy was a country severely hit by the first coronavirus disease 2019 (COVID-19) pandemic wave in early 2020. Mortality studies have focused on the overall excess mortality observed during the pandemic. This paper investigates the cause-specific mortality in Italy from March 2020 to April 2020 and the variation in mortality rates compared with those in 2015-2019 regarding sex, age, and epidemic area. Causes of death were derived from the national cause-of-death register. COVID-19 was the leading cause of death among males and the second leading cause among females. Chronic diseases, such as diabetes and hypertensive, ischemic heart, and cerebrovascular diseases, with decreasing or stable mortality rates in 2015-2019, showed a reversal in the mortality trend. Moreover, mortality due to pneumonia and influenza increased. No increase in neoplasm mortality was observed. Among external causes of death, mortality increased for accidental falls but reduced for transport accidents and suicide. Mortality from causes other than COVID-19 increased similarly in both genders and more at ages 65 years or above. Compared with other areas in Italy, the Lombardy region showed the largest excess in mortality for all leading causes. Underdiagnosis of COVID-19 at the beginning of the pandemic may, to some extent, explain the mortality increase for some causes of death, especially pneumonia and other respiratory diseases.

Indexed as

COVID-19AgedCause of DeathFemaleHumansItalyMaleMortalityPandemicsSARS-CoV-2causes of deathCOVID-19Italymortalitypandemic

Identifiers

PMID35055627
PMCPMC8776013

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.