Evidence map›Paper›PMID 35055537›Full record

ArticleInternational journal of environmental research and public health2022

Dynamic of Glucose Homeostasis in Virtual Patients: A Comparison between Different Behaviors.

Alexis Alonso-Bastida, Manuel Adam-Medina, Rubén Posada-Gómez, Dolores Azucena Salazar-Piña, Gloria-Lilia Osorio-Gordillo, Luis Gerardo Vela-Valdés

Abstract read
In one paragraph

Article in International journal of environmental research and public health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Alexis Alonso-BastidaElectronic Engineering Department, TecNM/CENIDET, Cuernavaca 62490, Morelos, Mexico.ORCID 0000-0001-8563-9767
Manuel Adam-MedinaElectronic Engineering Department, TecNM/CENIDET, Cuernavaca 62490, Morelos, Mexico.ORCID 0000-0002-8106-3673
Rubén Posada-GómezTecNM/CRODE, Orizaba 94380, Veracruz, Mexico.ORCID 0000-0001-9325-7988
Dolores Azucena Salazar-PiñaFaculty of Nutrition, UAEM, Cuernavaca 62350, Morelos, Mexico.ORCID 0000-0003-0800-7226
Gloria-Lilia Osorio-GordilloElectronic Engineering Department, TecNM/CENIDET, Cuernavaca 62490, Morelos, Mexico.ORCID 0000-0002-3445-8867
Luis Gerardo Vela-ValdésElectronic Engineering Department, TecNM/CENIDET, Cuernavaca 62490, Morelos, Mexico.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This work presents a mathematical model of homeostasis dynamics in healthy individuals, focusing on the generation of conductive data on glucose homeostasis throughout the day under dietary and physical activity factors. Two case studies on glucose dynamics for populations under conditions of physical activity and sedentary lifestyle were developed. For this purpose, two types of virtual populations were generated, the first population was developed according to the data of a total of 89 physical persons between 20 and 75 years old and the second was developed using the Monte Carlo approach, obtaining a total of 200 virtual patients. In both populations, each participant was classified as an active or sedentary person depending on the physical activity performed. The results obtained demonstrate the capacity of virtual populations in the generation of in-silico approximations similar to those obtained from in-vivo studies. Obtaining information that is only achievable through specific in-vivo experiments. Being a tool that generates information for the approach of alternatives in the prevention of the development of type 2 Diabetes.

Indexed as

Diabetes Mellitus, Type 2AdultAgedBlood GlucoseExerciseGlucoseHomeostasisHumansMiddle AgedYoung AdultBlood GlucoseGlucosedaily activitiesextended Bergman minimal modelglucose homeostasisMonte Carlo approach

Identifiers

PMID35055537
PMCPMC8775377

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.