Evidence map›Paper›PMID 35055501›Full record

ArticleInternational journal of environmental research and public health2022

Consumption of Sugar-Sweetened or Artificially Sweetened Beverages and Semen Quality in Young Men: A Cross-Sectional Study.

Maiken Meldgaard, Nis Brix, Anne Gaml-Sørensen, Andreas Ernst, Cecilia Høst Ramlau-Hansen, Sandra Søgaard Tøttenborg, Karin Sørig Hougaard, Jens Peter Ellekilde Bonde, Gunnar Toft

Abstract read
In one paragraph

Article in International journal of environmental research and public health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. How Food Choices Impact on Male Fertility.Current nutrition reports · 2023
    Review
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Maiken MeldgaardUnit for Applied Public Health, Department of Public Health, Research, Aarhus University, 8000 Aarhus, Denmark.ORCID 0000-0003-4122-1793
Nis BrixResearch Unit for Epidemiology, Department of Public Health, Aarhus University, 8000 Aarhus, Denmark.
Anne Gaml-SørensenResearch Unit for Epidemiology, Department of Public Health, Aarhus University, 8000 Aarhus, Denmark.ORCID 0000-0002-5242-939X
Andreas ErnstResearch Unit for Epidemiology, Department of Public Health, Aarhus University, 8000 Aarhus, Denmark.
Cecilia Høst Ramlau-HansenResearch Unit for Epidemiology, Department of Public Health, Aarhus University, 8000 Aarhus, Denmark.ORCID 0000-0003-3296-0121
Sandra Søgaard TøttenborgDepartment of Occupational and Environmental Medicine, Bispebjerg and Frederiksberg Hospital, 2400 Copenhagen, Denmark.ORCID 0000-0001-7742-4360
Karin Sørig HougaardDenmark and National Research Centre for the Working Environment, Department of Public Health, University of Copenhagen, 1353 Copenhagen, Denmark.
Jens Peter Ellekilde BondeDepartment of Occupational and Environmental Medicine, Bispebjerg and Frederiksberg Hospital, 2400 Copenhagen, Denmark.
Gunnar ToftSteno Diabetes Center Aarhus, Aarhus University Hospital, 8200 Aarhus, Denmark.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundExisting literature suggests that frequent consumption of sugar-sweetened drinks may be associated with lower semen quality. Studies performed in mice suggest a dose-response relationship between intake of saccharin or aspartame, two artificial sweeteners, and sperm and testis function.

methodsA cross-sectional study based on data from The Fetal Programming of Semen Quality (FEPOS) Cohort, including 1047 young men (mean age = 19 years) was performed. Each male participant completed an online questionnaire on health, health behavior and diet, and provided a semen sample. The associations between consumption of sugar-sweetened or artificially sweetened beverages (moderate ≥ 3 days/week; infrequent < 3 days/week) and semen quality were analyzed using a multivariable, negative, binomial regression model.

resultsSugar-sweetened or artificially sweetened beverage consumption was not strongly associated with either semen volume, sperm concentration, total sperm count or total motility in young men. The proportion of morphologically normal sperm was 11% lower (0.89 (95% CI 0.76, 1.04)) for moderate (≥3 days/week) consumption of artificially sweetened beverages relative to infrequent (<3 days/week).

conclusionConsumption of sugar-sweetened or artificially sweetened beverages, at the levels present in this study had limited effect on the measured markers of semen quality in young men.

Indexed as

Artificially Sweetened BeveragesSweetening AgentsAnimalsBeveragesCross-Sectional StudiesHumansMaleMiceSemen AnalysisSugarsSugarsSweetening Agentsbeverage consumptionnon-nutritive sweetenersemen qualitysoft drinksperm morphology

Identifiers

PMID35055501
PMCPMC8775653

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.