Evidence map›Paper›PMID 35055425›Full record

ArticleJournal of personalized medicine2022

The Relationship between Epigenetic Age and Myocardial Infarction/Acute Coronary Syndrome in a Population-Based Nested Case-Control Study.

Sofia Malyutina, Olga Chervova, Taavi Tillmann, Vladimir Maximov, Andrew Ryabikov, Valery Gafarov, Jaroslav A Hubacek, Hynek Pikhart, Stephan Beck, Martin Bobak

Abstract read
In one paragraph

Article in Journal of personalized medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Sofia MalyutinaResearch Institute of Internal and Preventive Medicine-Branch of Institute of Cytology and Genetics SB RAS, 630089 Novosibirsk, Russia.ORCID 0000-0001-6539-0466
Olga ChervovaUCL Cancer Institute, University College London, London WC1E 6BT, UK.ORCID 0000-0002-1671-9488
Taavi TillmannInstitute for Global Health, University College London, London WC1E 6BT, UK.
Vladimir MaximovResearch Institute of Internal and Preventive Medicine-Branch of Institute of Cytology and Genetics SB RAS, 630089 Novosibirsk, Russia.ORCID 0000-0002-7165-4496
Andrew RyabikovResearch Institute of Internal and Preventive Medicine-Branch of Institute of Cytology and Genetics SB RAS, 630089 Novosibirsk, Russia.
Valery GafarovResearch Institute of Internal and Preventive Medicine-Branch of Institute of Cytology and Genetics SB RAS, 630089 Novosibirsk, Russia.
Jaroslav A HubacekExperimental Medicine Centre, Institute for Clinical and Experimental Medicine, 14021 Prague, Czech Republic.ORCID 0000-0001-6537-1353
Hynek PikhartInstitute of Epidemiology and Health Care, University College London, London WC1E 6BT, UK.
Stephan BeckUCL Cancer Institute, University College London, London WC1E 6BT, UK.
Martin BobakInstitute of Epidemiology and Health Care, University College London, London WC1E 6BT, UK.

Funding

Russian Scientific Foundation 20-15-00371US National Institute of Aging 1RO1AG23522Welcome Trust 106554/Z/14/ZWelcome Trust WT064947Welcome Trust WT081081
6 · The paper itself

Abstract

We investigated the relationship between 'epigenetic age' (EA) derived from DNA methylation (DNAm) and myocardial infarction (MI)/acute coronary syndrome (ACS). A random population sample was examined in 2003/2005 (

Indexed as

acute coronary syndromeDNA methylationepigenetic ageHAPIEE projectmyocardial infarctionnested case-controlpopulation

Identifiers

PMID35055425
PMCPMC8781885

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.