Evidence map›Paper›PMID 35055424›Full record

ArticleJournal of personalized medicine2022

Machine Learning-Based Approaches for Prediction of Patients' Functional Outcome and Mortality after Spontaneous Intracerebral Hemorrhage.

Rui Guo, Renjie Zhang, Ran Liu, Yi Liu, Hao Li, Lu Ma, Min He, Chao You, Rui Tian

Registry-linked trialAbstract read
In one paragraph

Article in Journal of personalized medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05424614 (Capital's Funds for Health Improvement and Research), which is not on this map. Cited by 20 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05424614 unknown statusnot on this map

Capital's Funds for Health Improvement and Research

TypeobservationalSponsorBeijing Neurosurgical InstituteRan2022 to 2024Enrolled150ConditionsCerebral Hemorrhage, Prognosis, Artificial IntelligenceArmsFunctional outcome follow-up of patients
3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 4 syntheses or guidelines pooled it.

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  16. Prediction of poor outcome in stroke patients using radiomics analysis of intraparenchymal and intraventricular hemorrhage and clinical factors.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Rui GuoDepartment of Neurosurgery, West China Hospital, Sichuan University, Chengdu 610041, China.
Renjie ZhangDepartment of Neurosurgery, West China Hospital, Sichuan University, Chengdu 610041, China.
Ran LiuEngineering Research Center of Medical Information Technology, Ministry of Education, West China Hospital, Sichuan University, Chengdu 610041, China.
Yi LiuDepartment of Neurosurgery, West China Hospital, Sichuan University, Chengdu 610041, China.
Hao LiDepartment of Neurosurgery, West China Hospital, Sichuan University, Chengdu 610041, China.
Lu MaDepartment of Neurosurgery, West China Hospital, Sichuan University, Chengdu 610041, China.
Min HeDepartment of Neurosurgery, West China Hospital, Sichuan University, Chengdu 610041, China.
Chao YouDepartment of Neurosurgery, West China Hospital, Sichuan University, Chengdu 610041, China.
Rui TianDepartment of Neurosurgery, West China Hospital, Sichuan University, Chengdu 610041, China.ORCID 0000-0003-0911-6766

Funding

1·3·5 Project for Disciplines of Excellence, West China Hospital, Sichuan University 2018HXFH0071·3·5 Project for Disciplines of Excellence, West China Hospital, Sichuan University 2018HXFH008Clinical Research Innovation Project, West China Hospital, Sichuan University 2019HXCX07National Key R&D Program of China 2018YFA0108603
6 · The paper itself

Abstract

Spontaneous intracerebral hemorrhage (SICH) has been common in China with high morbidity and mortality rates. This study aims to develop a machine learning (ML)-based predictive model for the 90-day evaluation after SICH. We retrospectively reviewed 751 patients with SICH diagnosis and analyzed clinical, radiographic, and laboratory data. A modified Rankin scale (mRS) of 0-2 was defined as a favorable functional outcome, while an mRS of 3-6 was defined as an unfavorable functional outcome. We evaluated 90-day functional outcome and mortality to develop six ML-based predictive models and compared their efficacy with a traditional risk stratification scale, the intracerebral hemorrhage (ICH) score. The predictive performance was evaluated by the areas under the receiver operating characteristic curves (AUC). A total of 553 patients (73.6%) reached the functional outcome at the 3rd month, with the 90-day mortality rate of 10.2%. Logistic regression (LR) and logistic regression CV (LRCV) showed the best predictive performance for functional outcome (AUC = 0.890 and 0.887, respectively), and category boosting presented the best predictive performance for the mortality (AUC = 0.841). Therefore, ML might be of potential assistance in the prediction of the prognosis of SICH.

Indexed as

90-day function outcomemachine learningmortalityspontaneous intracerebral hemorrhage (SICH)

Identifiers

PMID35055424
PMCPMC8778760

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.