Evidence map›Paper›PMID 35055421›Full record

ArticleJournal of personalized medicine2022

Relevant Biomarkers in Medical Practices: An Analysis of the Needs Addressed by an International Survey.

Laure Abensur Vuillaume, Thierry Leichle, Pierrick Le Borgne, Mathieu Grajoszex, Christophe Goetz, Paul L Voss, Abdallah Ougazzaden, Jean-Paul Salvestrini, Marie-Pia d'Ortho

Abstract read
In one paragraph

Article in Journal of personalized medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. The use of biomarkers testing in Emergency Department.Journal of critical care medicine (Universitatea de Medicina si Farmacie din Targu-Mures) · 2025
    Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Laure Abensur VuillaumeEmergency Department CHR Metz-Thionville, 57000 Metz, France.ORCID 0000-0003-2527-8458
Thierry LeichleCNRS, IRL 2958, GT-CNRS, 2 Rue Marconi, LAV, 57070 Metz, France.
Pierrick Le BorgneEmergency Department, Hopitaux Universitaires de Strasbourg, 67000 Strasbourg, France.ORCID 0000-0001-9141-6439
Mathieu GrajoszexDigital Medical Hub, APHP, 75000 Paris, France.
Christophe GoetzClinical Research Support Unit, CHR Metz-Thionville, 57000 Metz, France.ORCID 0000-0002-8381-2607
Paul L VossCNRS, IRL 2958, GT-CNRS, 2 Rue Marconi, LAV, 57070 Metz, France.
Abdallah OugazzadenCNRS, IRL 2958, GT-CNRS, 2 Rue Marconi, LAV, 57070 Metz, France.
Jean-Paul SalvestriniCNRS, IRL 2958, GT-CNRS, 2 Rue Marconi, LAV, 57070 Metz, France.
Marie-Pia d'OrthoDigital Medical Hub, APHP, 75000 Paris, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

(1) Backround: Technological advances should foster gains in physicians' efficiency. For example, a reduction of the medical decision time can be enabled by faster biological tests. The main objective of this study was to collect responses from an international panel of physicians on their needs for biomarkers and also to convey the improvement in the outcome to be made possible by the potential development of fast diagnostic tests for these biomarkers. (2) Methods: we distributed a questionnaire on the Internet to physicians. (3) Results: 508 physicians participated in this survey. The mean age was 38 years. General practice and emergency medicine were heavily represented, with 95% CIs of 44% (39.78, 48.41) and 32% (27.84, 35.94)), respectively. The two most represented countries were France (95% CI: 74% (70.20, 77.83)) and the USA (95% CI: 11% (8.65, 14.18)). Ninety-eight percentages of the physicians thought that obtaining cited biomarkers more quickly would be beneficial to their practice and to patient's care. The main biomarkers of interest identified by our panel were troponin (95% CI: 51% (46.24, 54.94)), C-reactive protein (95% CI: 42% (38.03, 46.62)), D-dimer (95% CI: 29% (24.80, 32.68)), and brain natriuretic peptide (95% CI: 13% (10.25, 16.13)). (4) Conclusions: Our study highlights the real technological need for fast biomarker results, which could be provided by biosensors. The relevance of some answers such as troponin is questionable.

Indexed as

biomarkersbiosensorsemergency overcrowding

Identifiers

PMID35055421
PMCPMC8778050

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.