ArticleJournal of personalized medicine2022
Clinical Management of Chronic Pelvic Pain in Endometriosis Unresponsive to Conventional Therapy.
Article in Journal of personalized medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- Enhancing Pain Management: The Role of Superior Hypogastric Plexus Block in Chronic Pelvic Pain Treatment.Journal of pharmacy & bioallied sciences · 2025Review
- Adjunctive Efficacy of Superior Hypogastric Plexus Block in Chronic Pelvic Pain: A Comprehensive Review.Journal of pharmacy & bioallied sciences · 2025Review
- Identification and validation of a novel machine learning model for predicting severe pelvic endometriosis: A retrospective study.Scientific reports · 2025Article
- Extracellular Trap-Related Genes as Potential Diagnostic Biomarkers for Endometriosis.International journal of women's health · 2025Article
- Anatomo-physiological basis and applied techniques of electrical neuromodulation in chronic pain.Journal of anesthesia, analgesia and critical care · 2024Review
- Registration and characteristics of clinical trials on traditional Chinese medicine and natural medicines for endometriosis: a comprehensive analysis.Frontiers in medicine · 2024Review
- Understanding the Female Physical Examination in Patients with Chronic Pelvic and Perineal Pain.Journal of clinical medicine · 2022Article
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Authors and funding
7 authors.
Funding
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Abstract
backgroundAlthough several treatments are currently available for chronic pelvic pain, 30-60% of patients do not respond to them. Therefore, these therapeutic options require a better understanding of the mechanisms underlying endometriosis-induced pain. This study focuses on pain management after failure of conventional therapy.
methodsWe reviewed clinical data from 46 patients with endometriosis and chronic pelvic pain unresponsive to conventional therapies at Puerta de Hierro University Hospital Madrid, Spain from 2018 to 2021. Demographic data, clinical and exploratory findings, treatment received, and outcomes were collected.
resultsMedian age was 41.5 years, and median pain intensity was VAS: 7.8/10. Nociceptive pain and neuropathic pain were identified in 98% and 70% of patients, respectively. The most common symptom was abdominal pain (78.2%) followed by pain with sexual intercourse (65.2%), rectal pain (52.1%), and urologic pain (36.9%). A total of 43% of patients responded to treatment with neuromodulators. Combined therapies for myofascial pain syndrome, as well as treatment of visceral pain with inferior or superior hypogastric plexus blocks, proved to be very beneficial. S3 pulsed radiofrequency (PRF) plus inferior hypogastric plexus block or botulinum toxin enabled us to prolong response time by more than 3.5 months.
conclusionTreatment of the unresponsive patient should be interdisciplinary. Depending on the history and exploratory findings, therapy should preferably be combined with neuromodulators, myofascial pain therapies, and S3 PRF plus inferior hypogastric plexus blockade.
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