Evidence map›Paper›PMID 35055406›Full record

ArticleJournal of personalized medicine2022

Incidence and Predictors of Infections and All-Cause Death in Patients with Cardiac Implantable Electronic Devices: The Italian Nationwide RI-AIAC Registry.

Giuseppe Boriani, Marco Proietti, Matteo Bertini, Igor Diemberger, Pietro Palmisano, Stefano Baccarini, Francesco Biscione, Nicola Bottoni, Antonio Ciccaglioni, Alessandro Dal Monte and 14 more

Open access · goldAbstract read
In one paragraph

Article in Journal of personalized medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 2 pooled it
5.1field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 2 syntheses or guidelines pooled it, 36 citations in OpenAlex.

  1. Pooled it
  2. Systematic review and meta-analysis on the impact on outcomes of device algorithms for minimizing right ventricular pacing.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2024
    Pooled it
  3. Article
  4. Validation of the PADIT (prevention of arrhythmia device infection trial) risk score for infection and infection subtypes.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2026
    Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Review
  11. Review
  12. Device infection in patients undergoing pacemaker or defibrillator surgery: risk stratification using the PADIT score.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2024
    Article
  13. Chronic kidney disease and transvenous cardiac implantable electronic device infection-is there an impact on healthcare utilization, costs, disease progression, and mortality?Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2024
    Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. REducing INFectiOns thRough Cardiac device Envelope: insight from real world data. The REINFORCE project.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2023
    Article
  19. Length of hospital stay for elective electrophysiological procedures: a survey from the European Heart Rhythm Association.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2023
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors at 13 institutions in 2 countries.

Giuseppe BorianiCardiology Division, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Policlinico di Modena, 41125 Modena, Italy.ORCID 0000-0002-9820-4815
Marco ProiettiGeriatric Unit, IRCCS Istituti Clinici Scientifici Maugeri, 20138 Milan, Italy.ORCID 0000-0003-1452-2478
Matteo BertiniCardiological Center, University of Ferrara, 44124 Ferrara, Italy.ORCID 0000-0002-5285-7140
Igor DiembergerDepartment of Experimental, Diagnostic and Specialty Medicine, Institute of Cardiology, University of Bologna, Policlinico S. Orsola-Malpighi, 40138 Bologna, Italy.
Pietro PalmisanoCardiology Unit, 'Card. Giovanni Panico' Hospital, 73039 Tricase, Italy.ORCID 0000-0001-6705-6218
Stefano BaccariniCardiology Unit, Emergency Department, Fidenza Hospital, 43036 Fidenza, Italy.
Francesco BiscioneCardiology Unit, Santo Spirito Hospital, 00193 Rome, Italy.
Nicola BottoniSanta Maria Nuova Hospital, 42123 Reggio Emilia, Italy.
Antonio CiccaglioniDepartment of Cardiovascular Sciences, Sapienza-University of Rome, 00161 Rome, Italy.
Alessandro Dal MonteCardiology Unit, Santa Maria delle Croci Hospital, 48121 Ravenna, Italy.
Franco Alberto FerrariCardiology Unit, Rho Hospital, 20017 Rho, Italy.
Saverio IacopinoElectrophysiology Unit, Maria Cecilia Hospital, 48033 Cotignola, Italy.ORCID 0000-0002-2131-1110
Marcello PiacentiFondazione Toscana 'Gabriele Monasterio', 56124 Pisa, Italy.
Daniele PorcelliArrhythmology Unit, Cardiology Department, S. Giovanni Calibita Fatebenefratelli Hospital, 00186 Rome, Italy.
Stefano SangiorgioElectrophysiology Unit, Fatebenefratelli Hospital, 20121 Milan, Italy.
Luca SantiniDepartment of Cardiology, Ospedale GB Grassi, 00122 Ostia, Italy.ORCID 0000-0001-9048-2039
Michele MalagùCardiological Center, University of Ferrara, 44124 Ferrara, Italy.ORCID 0000-0002-1972-9665
Giuseppe StabileDepartment of Cardiology, Clinica Montevergine, 83013 Mercogliano, Italy.
Jacopo Francesco ImbertiCardiology Division, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Policlinico di Modena, 41125 Modena, Italy.ORCID 0000-0003-3403-3364
Davide CarusoPadre Antero Micone Hospital, ASL 3 "Genovese", 16153 Genova, Italy.
Massimo Zoni-BerissoPadre Antero Micone Hospital, ASL 3 "Genovese", 16153 Genova, Italy.
Roberto De PontiCardiovascular Department, Circolo Hospital, University of Insubria, 21100 Varese, Italy.ORCID 0000-0003-3278-1721
Renato Pietro RicciCardioArrhythmology Center, 00152 Rome, Italy.
On Behalf Of Ri-Aiac Registry Investigators
Fatebenefratelli Hospital · ITUniversity of Ferrara · ITUniversity of Modena and Reggio Emilia · ITCTO Hospital · ITFondazione Toscana Gabriele Monasterio · ITIRCCS Azienda Ospedliero-Universitaria di Bologna Policlinico di Sant'Orsola · ITMaria Cecilia Hospital · ITOspedale di Santo Spirito · ITOspedale "Santa Maria delle Croci" di Ravenna · ITSanta Maria Nuova Hospital · ITSapienza University of Rome · ITUniversity of Insubria · ITUniversity of Liverpool · GB

Funding

Medtronic (Italy) NA
6 · The paper itself

Abstract

backgroundThe incidence of infections associated with cardiac implantable electronic devices (CIEDs) and patient outcomes are not fully known.

aimTo provide a contemporary assessment of the risk of CIEDs infection and associated clinical outcomes.

methodsIn Italy, 18 centres enrolled all consecutive patients undergoing a CIED procedure and entered a 12-months follow-up. CIED infections, as well as a composite clinical event of infection or all-cause death were recorded.

resultsA total of 2675 patients (64.3% male, age 78 (70-84)) were enrolled. During follow up 28 (1.1%) CIED infections and 132 (5%) deaths, with 152 (5.7%) composite clinical events were observed. At a multivariate analysis, the type of procedure (revision/upgrading/reimplantation) (OR: 4.08, 95% CI: 1.38-12.08) and diabetes (OR: 2.22, 95% CI: 1.02-4.84) were found as main clinical factors associated to CIED infection. Both the PADIT score and the RI-AIAC Infection score were significantly associated with CIED infections, with the RI-AIAC infection score showing the strongest association (OR: 2.38, 95% CI: 1.60-3.55 for each point), with a c-index = 0.64 (0.52-0.75),

conclusionsIn this Italian nationwide cohort of patients, while the incidence of CIED infections was substantially low, the rate of the composite clinical outcome of infection or all-cause death was quite high and associated with several clinical factors depicting a more impaired clinical status.

Indexed as

cardiac implantable electronic deviceimplantable defibrillatorinfectionoutcomepacemaker

Identifiers

PMID35055406
PMCPMC8780465
OpenAlexW4206086302

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.