Evidence map›Paper›PMID 35055364›Full record

ArticleJournal of personalized medicine2022

Microbiome Changes in Humans with Parkinson's Disease after Photobiomodulation Therapy: A Retrospective Study.

Brian Bicknell, Ann Liebert, Craig S McLachlan, Hosen Kiat

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of personalized medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Brian BicknellFaculty of Health Sciences, Australian Catholic University, 40 Edward St, Sydney, NSW 2060, Australia.
Ann LiebertResearch Governance Office, Sydney Adventist Hospital, 185 Fox Valley Rd, Sydney, NSW 2076, Australia.
Craig S McLachlanCentre for Healthy Futures, Torrens University, Sydney, NSW 2000, Australia.
Hosen KiatCentre for Healthy Futures, Torrens University, Sydney, NSW 2000, Australia.ORCID 0000-0002-2899-118X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

There is a paucity of information on the effect of photobiomodulation therapy on gut microbiome composition. Parkinson's disease is a progressive neurological disorder with few management options, although the gut microbiome has been suggested as a potential avenue of treatment. We retrospectively analysed the microbiome from human stool samples from a previously published study, which had demonstrated the efficacy of photobiomodulation to treat Parkinson's patients' symptoms. Specifically, we have observed changes in the microbiome of Parkinson's patients after a 12-week treatment regimen with photobiomodulation to the abdomen, neck, head and nose. Noted were positive changes in the Firmicutes to Bacteroidetes (F:B) ratio, which is often interpreted as a proxy for gut health.

Indexed as

microbiomeParkinson’s diseasephotobiomodulation

Identifiers

PMID35055364
PMCPMC8778696

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.