Evidence map›Paper›PMID 35055297›Full record

ArticleNanomaterials (Basel, Switzerland)2022

Contrast Enhanced Ultrasound Molecular Imaging of Spontaneous Chronic Inflammatory Bowel Disease in an Interleukin-2 Receptor α

Huaijun Wang, Jose G Vilches-Moure, Thierry Bettinger, Samir Cherkaoui, Amelie Lutz, Ramasamy Paulmurugan

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nanomaterials (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Huaijun WangDepartment of Radiology, School of Medicine, Stanford University, Palo Alto, CA 94304, USA.
Jose G Vilches-MoureDepartment of Comparative Medicine, Stanford University, Stanford, CA 94305, USA.
Thierry BettingerBracco Suisse SA, 1201 Geneva, Switzerland.
Samir CherkaouiBracco Suisse SA, 1201 Geneva, Switzerland.
Amelie LutzDepartment of Radiology, School of Medicine, Stanford University, Palo Alto, CA 94304, USA.
Ramasamy PaulmuruganDepartment of Radiology, School of Medicine, Stanford University, Palo Alto, CA 94304, USA.ORCID 0000-0001-7155-4738
Stanford University · USBracco (Switzerland) · CH

Funding

National Institute of Health R01CA209888; R21EB022298
6 · The paper itself

Abstract

Inflammatory bowel disease (IBD) is a lifelong inflammatory disorder with relapsing-remission cycles, which is currently diagnosed by clinical symptoms and signs, along with laboratory and imaging findings. However, such clinical findings are not parallel to the disease activity of IBD and are difficult to use in treatment monitoring. Therefore, non-invasive quantitative imaging tools are required for the multiple follow-up exams of IBD patients in order to monitor the disease activity and determine treatment regimens. In this study, we evaluated a dual P- and E-selectin-targeted microbubble (MB

Indexed as

chronic diseasecolitisE-selectinflareinflammatory bowel disease (IBD)interleukin 2 receptor α deficient (IL-2Rα−/−) miceP-selectinremissiontransgenic mouse modelultrasound molecular imaging (USMI)

Identifiers

PMID35055297
PMCPMC8779209
OpenAlexW4205491122

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.