Evidence map›Paper›PMID 35055185›Full record

ArticleInternational journal of molecular sciences2022

Maternal Fructose Intake Causes Developmental Reprogramming of Hepatic Mitochondrial Catalytic Activity and Lipid Metabolism in Weanling and Young Adult Offspring.

Erin Vanessa LaRae Smith, Rebecca Maree Dyson, Christina M G Vanderboor, Ousseynou Sarr, Jane Anderson, Mary J Berry, Timothy R H Regnault, Lifeng Peng, Clint Gray

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
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  8. Review
  9. Early Life Nutrition and the Development of Offspring Metabolic Health.International journal of molecular sciences · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Erin Vanessa LaRae SmithDepartment of Paediatrics and Child Health, University of Otago, Wellington 6021, New Zealand.ORCID 0000-0002-0477-0569
Rebecca Maree DysonDepartment of Paediatrics and Child Health, University of Otago, Wellington 6021, New Zealand.ORCID 0000-0003-2319-6897
Christina M G VanderboorDepartment of Physiology and Pharmacology, Western University, London, ON N6A 3K7, Canada.
Ousseynou SarrDepartment of Physiology and Pharmacology, Western University, London, ON N6A 3K7, Canada.
Jane AndersonDepartment of Pathology & Molecular Medicine, University of Otago, Wellington 6021, New Zealand.
Mary J BerryDepartment of Paediatrics and Child Health, University of Otago, Wellington 6021, New Zealand.ORCID 0000-0001-9798-6790
Timothy R H RegnaultDepartment of Obstetrics and Gynaecology, Children's Health Research Institute, Western University, London, ON N6A 3K7, Canada.ORCID 0000-0003-1930-8358
Lifeng PengCentre for Biodiscovery and School of Biological Sciences, Victoria University of Wellington, Wellington 6021, New Zealand.
Clint GrayDepartment of Paediatrics and Child Health, University of Otago, Wellington 6021, New Zealand.
University of Otago · NZWestern University · CAVictoria University of Wellington · NZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Excess dietary fructose is a major public health concern, yet little is known about its influence on offspring development and later-life disease when consumed in excess during pregnancy. To determine whether increased maternal fructose intake could have long-term consequences on offspring health, we investigated the effects of 10%

Indexed as

AnimalsChromatography, LiquidElectron Transport Chain Complex ProteinsFatty Acids, MonounsaturatedFemaleFructoseGuinea PigsHumansLipid MetabolismMaleMitochondria, LiverOxidative PhosphorylationPregnancyPrenatal Exposure Delayed EffectsProteomicsReactive Oxygen SpeciesElectron Transport Chain Complex ProteinsFatty Acids, MonounsaturatedFructosepalmitoleic acidReactive Oxygen SpeciesTriglyceridesdevelopmental programmingexcess fructose intakehepatic metabolismmaternal fructosemitochondrial functionmitochondrial metabolism

Identifiers

PMID35055185
PMCPMC8780605
OpenAlexW4205755076

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.