Evidence map›Paper›PMID 35055082›Full record

ArticleInternational journal of molecular sciences2022

NGF Enhances CGRP Release Evoked by Capsaicin from Rat Trigeminal Neurons: Differential Inhibition by SNAP-25-Cleaving Proteases.

Mariia Belinskaia, Tomas Zurawski, Seshu Kumar Kaza, Caren Antoniazzi, J Oliver Dolly, Gary W Lawrence

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Observational
  6. Article
  7. Article
  8. Article
  9. Article
  10. OnabotulinumtoxinA effects on trigeminal nociceptors.Cephalalgia : an international journal of headache · 2023
    Article
  11. Review
  12. Article
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Mariia BelinskaiaInternational Centre for Neurotherapeutics, Dublin City University, Collins Avenue, D09 V209 Dublin, Ireland.ORCID 0000-0003-1326-4948
Tomas ZurawskiInternational Centre for Neurotherapeutics, Dublin City University, Collins Avenue, D09 V209 Dublin, Ireland.
Seshu Kumar KazaInternational Centre for Neurotherapeutics, Dublin City University, Collins Avenue, D09 V209 Dublin, Ireland.
Caren AntoniazziInternational Centre for Neurotherapeutics, Dublin City University, Collins Avenue, D09 V209 Dublin, Ireland.ORCID 0000-0003-4285-8956
J Oliver DollyInternational Centre for Neurotherapeutics, Dublin City University, Collins Avenue, D09 V209 Dublin, Ireland.
Gary W LawrenceInternational Centre for Neurotherapeutics, Dublin City University, Collins Avenue, D09 V209 Dublin, Ireland.
Dublin City University · IE

Funding

Science Foundation Ireland 15/IA/3026
6 · The paper itself

Abstract

Nerve growth factor (NGF) is known to intensify pain in various ways, so perturbing pertinent effects without negating its essential influences on neuronal functions could help the search for much-needed analgesics. Towards this goal, cultured neurons from neonatal rat trigeminal ganglia-a locus for craniofacial sensory nerves-were used to examine how NGF affects the Ca

Indexed as

AnimalsBotulinum Toxins, Type ACalcitonin Gene-Related PeptideCalciumCalcium SignalingCapsaicinDose-Response Relationship, DrugExocytosisNerve Growth FactorProteolysisRatsSensory Receptor CellsSynaptosomal-Associated Protein 25Trigeminal GanglionBotulinum Toxins, Type ACalcitonin Gene-Related PeptideCalciumCapsaicinNerve Growth FactorSynaptosomal-Associated Protein 25botulinum neurotoxinscalcitonin gene-related peptidecapsaicinchimeric neurotoxinnerve growth factornociceptor sensitisationtrigeminal ganglion neuronsTRPV1

Identifiers

PMID35055082
PMCPMC8778182
OpenAlexW4205787184

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.