Evidence map›Paper›PMID 35055072›Full record

ArticleInternational journal of molecular sciences2022

Validating Reference Gene Expression Stability in Human Ovarian Follicles, Oocytes, Cumulus Cells, Ovarian Medulla, and Ovarian Cortex Tissue.

Jesús Cadenas, Susanne Elisabeth Pors, Dmitry Nikiforov, Mengxue Zheng, Cristina Subiran, Jane Alrø Bøtkjær, Linn Salto Mamsen, Stine Gry Kristensen, Claus Yding Andersen

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 25 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Jesús CadenasLaboratory of Reproductive Biology, The Juliane Marie Centre for Women, Children and Reproduction, University Hospital of Copenhagen, Rigshospitalet, 2100 Copenhagen, Denmark.ORCID 0000-0001-8164-3697
Susanne Elisabeth PorsLaboratory of Reproductive Biology, The Juliane Marie Centre for Women, Children and Reproduction, University Hospital of Copenhagen, Rigshospitalet, 2100 Copenhagen, Denmark.ORCID 0000-0003-1546-1945
Dmitry NikiforovLaboratory of Reproductive Biology, The Juliane Marie Centre for Women, Children and Reproduction, University Hospital of Copenhagen, Rigshospitalet, 2100 Copenhagen, Denmark.
Mengxue ZhengLaboratory of Reproductive Biology, The Juliane Marie Centre for Women, Children and Reproduction, University Hospital of Copenhagen, Rigshospitalet, 2100 Copenhagen, Denmark.
Cristina SubiranLaboratory of Reproductive Biology, The Juliane Marie Centre for Women, Children and Reproduction, University Hospital of Copenhagen, Rigshospitalet, 2100 Copenhagen, Denmark.
Jane Alrø BøtkjærLaboratory of Reproductive Biology, The Juliane Marie Centre for Women, Children and Reproduction, University Hospital of Copenhagen, Rigshospitalet, 2100 Copenhagen, Denmark.
Linn Salto MamsenLaboratory of Reproductive Biology, The Juliane Marie Centre for Women, Children and Reproduction, University Hospital of Copenhagen, Rigshospitalet, 2100 Copenhagen, Denmark.
Stine Gry KristensenLaboratory of Reproductive Biology, The Juliane Marie Centre for Women, Children and Reproduction, University Hospital of Copenhagen, Rigshospitalet, 2100 Copenhagen, Denmark.ORCID 0000-0003-1194-8393
Claus Yding AndersenLaboratory of Reproductive Biology, The Juliane Marie Centre for Women, Children and Reproduction, University Hospital of Copenhagen, Rigshospitalet, 2100 Copenhagen, Denmark.
Rigshospitalet · DK

Funding

Independent Research Fund Denmark 0134-00448
6 · The paper itself

Abstract

Human ovarian cells are phenotypically very different and are often only available in limited amounts. Despite the fact that reference gene (RG) expression stability has been validated in oocytes and other ovarian cells from several animal species, the suitability of a single universal RG in the different human ovarian cells and tissues has not been determined. The present study aimed to validate the expression stability of five of the most used RGs in human oocytes, cumulus cells, preantral follicles, ovarian medulla, and ovarian cortex tissue. The selected genes were glyceraldehyde 3-phosphate dehydrogenase (

Indexed as

BiomarkersGene Expression RegulationCumulus CellsFemaleGene Expression ProfilingHumansOocytesOvarian FollicleOvaryRNA StabilityTranscriptomeBiomarkershousekeeping geneshuman oocytesNormFinderovarian tissuepreantral folliclesquantitative real-time PCR

Identifiers

PMID35055072
PMCPMC8778884
OpenAlexW4206540546

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.