Evidence map›Paper›PMID 35055050›Full record

ReviewInternational journal of molecular sciences2022

Consequences of COVID-19 for the Pancreas.

Urszula Abramczyk, Maciej Nowaczyński, Adam Słomczyński, Piotr Wojnicz, Piotr Zatyka, Aleksandra Kuzan

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
5.8field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 58 citations in OpenAlex.

  1. Observational
  2. Article
  3. Review
  4. Review
  5. Review
  6. Implications of Dysnatremia and Endocrine Disturbances in COVID-19 Patients.International journal of molecular sciences · 2024
    Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Association of COVID with Mycosis in General.Infectious disorders drug targets · 2024
    Review
  14. Review
  15. Review
  16. Article
  17. Review
  18. Review
  19. Review
  20. The Pancreas in Coronavirus Disease 2019 Infection.Gastroenterology clinics of North America · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Urszula AbramczykDepartment of Medical Biochemistry, Wroclaw Medical University, 50-368 Wroclaw, Poland.ORCID 0000-0002-1697-2854
Maciej NowaczyńskiFaculty of Medicine, Wroclaw Medical University, 50-368 Wroclaw, Poland.
Adam SłomczyńskiFaculty of Medicine, Wroclaw Medical University, 50-368 Wroclaw, Poland.
Piotr WojniczFaculty of Medicine, Wroclaw Medical University, 50-368 Wroclaw, Poland.
Piotr ZatykaFaculty of Medicine, Wroclaw Medical University, 50-368 Wroclaw, Poland.
Aleksandra KuzanDepartment of Medical Biochemistry, Wroclaw Medical University, 50-368 Wroclaw, Poland.ORCID 0000-0003-4264-8174
Wroclaw Medical University · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although coronavirus disease 2019 (COVID-19)-related major health consequences involve the lungs, a growing body of evidence indicates that COVID-19 is not inert to the pancreas either. This review presents a summary of the molecular mechanisms involved in the development of pancreatic dysfunction during the course of COVID-19, the comparison of the effects of non-severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) on pancreatic function, and a summary of how drugs used in COVID-19 treatment may affect this organ. It appears that diabetes is not only a condition that predisposes a patient to suffer from more severe COVID-19, but it may also develop as a consequence of infection with this virus. Some SARS-CoV-2 inpatients experience acute pancreatitis due to direct infection of the tissue with the virus or due to systemic multiple organ dysfunction syndrome (MODS) accompanied by elevated levels of amylase and lipase. There are also reports that reveal a relationship between the development and treatment of pancreatic cancer and SARS-CoV-2 infection. It has been postulated that evaluation of pancreatic function should be increased in post-COVID-19 patients, both adults and children.

Indexed as

COVID-19 Drug TreatmentAngiotensin-Converting Enzyme 2COVID-19Diabetes ComplicationsDiabetes MellitusHumansMiddle East Respiratory Syndrome CoronavirusPancreasPancreatic NeoplasmsPancreatitisSerine EndopeptidasesSevere acute respiratory syndrome-related coronavirusSodium-Hydrogen ExchangersACE2 protein, humanAngiotensin-Converting Enzyme 2Serine EndopeptidasesSodium-Hydrogen ExchangersTMPRSS2 protein, humanCOVID-19diabetespancreasSARS-CoV-2

Identifiers

PMID35055050
PMCPMC8776154
OpenAlexW4206459770

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.