Evidence map›Paper›PMID 35055048›Full record

ArticleInternational journal of molecular sciences2022

Diet Prevents Social Stress-Induced Maladaptive Neurobehavioural and Gut Microbiota Changes in a Histamine-Dependent Manner.

Alessia Costa, Barbara Rani, Thomaz F S Bastiaanssen, Francesco Bonfiglio, Eoin Gunnigle, Gustavo Provensi, Moira Rossitto, Marcus Boehme, Conall Strain, Clara S Martínez and 5 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Teleosts as behaviour test models for social stress.Frontiers in behavioral neuroscience · 2023
    Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 3 institutions in 3 countries.

Alessia CostaDipartimento di Scienze della Salute, Universitá di Firenze, Viale Pieraccini 6, 50139 Firenze, Italy.ORCID 0000-0002-3693-3019
Barbara RaniDipartimento di Scienze della Salute, Universitá di Firenze, Viale Pieraccini 6, 50139 Firenze, Italy.ORCID 0000-0002-5602-7021
Thomaz F S BastiaanssenAPC Microbiome Ireland, University College Cork, T12 YT20 Cork, Ireland.ORCID 0000-0001-6891-734X
Francesco BonfiglioDipartimento di Neuroscienze, Psicologia, Area del Farmaco e Salute del Bambino (NEUROFARBA), Universitá di Firenze, Viale Pieraccini 6, 50139 Firenze, Italy.
Eoin GunnigleAPC Microbiome Ireland, University College Cork, T12 YT20 Cork, Ireland.
Gustavo ProvensiDipartimento di Neuroscienze, Psicologia, Area del Farmaco e Salute del Bambino (NEUROFARBA), Universitá di Firenze, Viale Pieraccini 6, 50139 Firenze, Italy.ORCID 0000-0002-6182-6848
Moira RossittoLaboratoire NutriNeuro, UMR INRAE, Bordeaux INP, Université de Bordeaux, 146 Rue Léo Saignat, 33076 Bordeaux, France.
Marcus BoehmeAPC Microbiome Ireland, University College Cork, T12 YT20 Cork, Ireland.
Conall StrainAPC Microbiome Ireland, University College Cork, T12 YT20 Cork, Ireland.
Clara S MartínezAPC Microbiome Ireland, University College Cork, T12 YT20 Cork, Ireland.
Patrizio BlandinaDipartimento di Neuroscienze, Psicologia, Area del Farmaco e Salute del Bambino (NEUROFARBA), Universitá di Firenze, Viale Pieraccini 6, 50139 Firenze, Italy.
John F CryanAPC Microbiome Ireland, University College Cork, T12 YT20 Cork, Ireland.ORCID 0000-0001-5887-2723
Sophie LayéLaboratoire NutriNeuro, UMR INRAE, Bordeaux INP, Université de Bordeaux, 146 Rue Léo Saignat, 33076 Bordeaux, France.ORCID 0000-0002-3843-1012
Renato CorradettiDipartimento di Neuroscienze, Psicologia, Area del Farmaco e Salute del Bambino (NEUROFARBA), Universitá di Firenze, Viale Pieraccini 6, 50139 Firenze, Italy.
Maria Beatrice PassaniDipartimento di Scienze della Salute, Universitá di Firenze, Viale Pieraccini 6, 50139 Firenze, Italy.ORCID 0000-0002-7729-9069
University of Florence · ITUniversity College Cork · IEUniversité de Bordeaux · FR

Funding

Fondation pour la Recherche Médicale FRM PRINSS DEQ20170336724JPI-Healthy Diet for Healthy Life Project AMBROSIAC
6 · The paper itself

Abstract

Exposure to repeated social stress may cause maladaptive emotional reactions that can be reduced by healthy nutritional supplementation. Histaminergic neurotransmission has a central role in orchestrating specific behavioural responses depending on the homeostatic state of a subject, but it remains to be established if it participates in the protective effects against the insults of chronic stress afforded by a healthy diet. By using C57BL/6J male mice that do not synthesize histamine (

Indexed as

DietDysbiosisGastrointestinal MicrobiomeSocial BehaviorStress, PsychologicalAnimalsBehavior, AnimalBiomarkersBody WeightCytokinesFatty AcidsGene ExpressionHippocampusHistamineLocomotionMaleBiomarkersCytokinesFatty AcidsHistamineHdc null micelong-term potentiationn-3 LC-PUFAoxylipinssocial avoidance

Identifiers

PMID35055048
PMCPMC8775792
OpenAlexW4205859226

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.