Evidence map›Paper›PMID 35055024›Full record

ReviewInternational journal of molecular sciences2022

Cancer Therapy by Silver Nanoparticles: Fiction or Reality?

Dávid Kovács, Nóra Igaz, Mohana K Gopisetty, Mónika Kiricsi

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 56 papers.

0numbers the graph read from it
0cells of the map it votes in
56citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

56 citing papers in PubMed.

  1. Enhanced anticancer efficacy ofMaterials today. Bio · 2026
    Article
  2. Review
  3. Article
  4. KCa3.1 mediates radioresistance of silver nanoparticles in human glioblastoma cells.Pflugers Archiv : European journal of physiology · 2026
    Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Review
  12. Article
  13. Review
  14. Article
  15. Frontiers in chemistry · 2026
    Article
  16. Article
  17. Plant-Mediated Fabrication of Silver Nanoparticles UsingBioinorganic chemistry and applications · 2026
    Article
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Dávid KovácsDepartment of Biochemistry and Molecular Biology, University of Szeged, Közép Fasor 52, H-6726 Szeged, Hungary.ORCID 0000-0002-5706-5126
Nóra IgazDepartment of Biochemistry and Molecular Biology, University of Szeged, Közép Fasor 52, H-6726 Szeged, Hungary.ORCID 0000-0003-1580-4397
Mohana K GopisettyDepartment of Biochemistry and Molecular Biology, University of Szeged, Közép Fasor 52, H-6726 Szeged, Hungary.
Mónika KiricsiDepartment of Biochemistry and Molecular Biology, University of Szeged, Közép Fasor 52, H-6726 Szeged, Hungary.ORCID 0000-0002-8416-2052

Funding

EC H2020 "METROFOOD-PP" (grant agreement No 871083)János Bolyai Research Scholarship of the Hungarian Academy of Sciences BO/00878/19/8National Research, Development, and Innovation Office-NKFIH GINOP-2.3.2-15-2016-00038, GINOP-2.3.2-15-2016-00035New National Excellence Program of the Ministry for Innovation and Technology ÚNKP-20-5-SZTE-655
6 · The paper itself

Abstract

As an emerging new class, metal nanoparticles and especially silver nanoparticles hold great potential in the field of cancer biology. Due to cancer-specific targeting, the consequently attenuated side-effects and the massive anti-cancer features render nanoparticle therapeutics desirable platforms for clinically relevant drug development. In this review, we highlight those characteristics of silver nanoparticle-based therapeutic concepts that are unique, exploitable, and achievable, as well as those that represent the critical hurdle in their advancement to clinical utilization. The collection of findings presented here will describe the features that distinguish silver nanoparticles from other anti-cancer agents and display the realistic opportunities and implications in oncotherapeutic innovations to find out whether cancer therapy by silver nanoparticles is fiction or reality.

Indexed as

Metal NanoparticlesNanomedicineSilverAnimalsAntineoplastic AgentsChemistry Techniques, SyntheticClinical Studies as TopicCombined Modality TherapyDisease ManagementDrug CarriersDrug CompoundingDrug Delivery SystemsDrug DevelopmentDrug Evaluation, PreclinicalHumansNanotechnologyAntineoplastic AgentsDrug CarriersSilvercancer therapymetal nanoparticlessilver nanoparticles

Identifiers

PMID35055024
PMCPMC8777983

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.