Evidence map›Paper›PMID 35054958›Full record

ArticleInternational journal of molecular sciences2022

The Veterinary Anti-Parasitic Selamectin Is a Novel Inhibitor of the

José Manuel Ezquerra-Aznárez, Giulia Degiacomi, Henrich Gašparovič, Giovanni Stelitano, Josè Camilla Sammartino, Jana Korduláková, Paolo Governa, Fabrizio Manetti, Maria Rosalia Pasca, Laurent Roberto Chiarelli and 1 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.0field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 20 citations in OpenAlex.

  1. Review
  2. ACS infectious diseases · 2025
    Article
  3. Article
  4. MedComm · 2023
    Review
  5. Selection of Multi-Drug Targets against Drug-ResistantInternational journal of molecular sciences · 2023
    Article
  6. Article
  7. Review
  8. Review
  9. New Drugs and Novel Cellular Targets against Tuberculosis.International journal of molecular sciences · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 3 countries.

José Manuel Ezquerra-AznárezDepartment of Microbiology, Faculty of Medicine, University of Zaragoza, 50009 Zaragoza, Spain.
Giulia DegiacomiDepartment of Biology and Biotechnology "Lazzaro Spallanzani", University of Pavia, 27100 Pavia, Italy.
Henrich GašparovičDepartment of Biochemistry, Faculty of Natural Sciences, Comenius University in Bratislava, 842 15 Bratislava, Slovakia.ORCID 0000-0002-4507-456X
Giovanni StelitanoDepartment of Biology and Biotechnology "Lazzaro Spallanzani", University of Pavia, 27100 Pavia, Italy.ORCID 0000-0002-5219-4770
Josè Camilla SammartinoDepartment of Biology and Biotechnology "Lazzaro Spallanzani", University of Pavia, 27100 Pavia, Italy.ORCID 0000-0003-3707-3118
Jana KordulákováDepartment of Biochemistry, Faculty of Natural Sciences, Comenius University in Bratislava, 842 15 Bratislava, Slovakia.ORCID 0000-0003-2834-0165
Paolo GovernaDepartment of Biotechnology, Chemistry and Pharmacy, University of Siena, 53100 Siena, Italy.ORCID 0000-0002-5976-780X
Fabrizio ManettiDepartment of Biotechnology, Chemistry and Pharmacy, University of Siena, 53100 Siena, Italy.ORCID 0000-0002-9598-2339
Maria Rosalia PascaDepartment of Biology and Biotechnology "Lazzaro Spallanzani", University of Pavia, 27100 Pavia, Italy.ORCID 0000-0002-8906-4937
Laurent Roberto ChiarelliDepartment of Biology and Biotechnology "Lazzaro Spallanzani", University of Pavia, 27100 Pavia, Italy.ORCID 0000-0003-0348-9764
Santiago Ramón-GarcíaDepartment of Microbiology, Faculty of Medicine, University of Zaragoza, 50009 Zaragoza, Spain.ORCID 0000-0002-8480-0325
University of Pavia · ITComenius University Bratislava · SKUniversidad de Zaragoza · ESUniversity of Siena · IT

Funding

Italian Ministry of University and Research Dipartimenti di Eccellenza Program, 2018-2022Slovak Research and Development Agency APVV-19-0189Spanish Government (Programa de Formación de Profesorado Universitario) FPU18/03873
6 · The paper itself

Abstract

Avermectins are macrocyclic lactones with anthelmintic activity. Recently, they were found to be effective against

Indexed as

Alcohol OxidoreductasesAmino Acid SequenceAntiparasitic AgentsAntitubercular AgentsBacterial ProteinsBinding SitesDose-Response Relationship, DrugDrug DiscoveryEnzyme InhibitorsIvermectinMicrobial Sensitivity TestsMolecular Docking SimulationMolecular Dynamics SimulationMutationMycobacterium tuberculosisStructure-Activity RelationshipAlcohol OxidoreductasesAntiparasitic AgentsAntitubercular AgentsBacterial ProteinsDprE1 protein, Mycobacterium tuberculosisEnzyme InhibitorsIvermectinselamectinavermectinsdrug repurposingMycobacterium tuberculosisselamectintuberculosis

Identifiers

PMID35054958
PMCPMC8776228
OpenAlexW4205292462

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.