Evidence map›Paper›PMID 35054928›Full record

ArticleInternational journal of molecular sciences2022

The Role of Cytoskeletal Proteins in the Formation of a Functional In Vitro Blood-Brain Barrier Model.

Shireen Mentor, Khayelihle Brian Makhathini, David Fisher

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.8field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. TheInternational journal of molecular sciences · 2022
    Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Shireen MentorNeurobiology Research Group, Department of Medical Biosciences, University of the Western Cape, Cape Town 7535, South Africa.ORCID 0000-0001-5430-0867
Khayelihle Brian MakhathiniNeurobiology Research Group, Department of Medical Biosciences, University of the Western Cape, Cape Town 7535, South Africa.
David FisherNeurobiology Research Group, Department of Medical Biosciences, University of the Western Cape, Cape Town 7535, South Africa.ORCID 0000-0001-6070-0234
University of the Western Cape · ZAUniversity of Missouri Health System · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The brain capillary endothelium is highly regulatory, maintaining the chemical stability of the brain's microenvironment. The role of cytoskeletal proteins in tethering nanotubules (TENTs) during barrier-genesis was investigated using the established immortalized mouse brain endothelial cell line (bEnd5) as an

Indexed as

ActinsAnimalsBiomarkersBlood-Brain BarrierCell LineCytoskeletal ProteinsEndothelial CellsEndothelium, VascularFluorescent Antibody TechniqueGene ExpressionMiceNocodazolePermeabilityActinsBiomarkersCytoskeletal ProteinsNocodazolebarrier-genesisbrain endothelial cellsCytochalasin DnanotubulesNocodazole

Identifiers

PMID35054928
PMCPMC8775705
OpenAlexW4206797743

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.