ReviewInternational journal of molecular sciences2022
Advances in 5-Aminolevulinic Acid Priming to Enhance Plant Tolerance to Abiotic Stress.
Review in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 72 citations in OpenAlex.
- 5-Aminolevulinic Acid Drives Coordinated Astaxanthin and Lipid Accumulation in Green AlgaFoods (Basel, Switzerland) · 2026Article
- Drill seeding and 5-ALA improve photosynthetic efficiency and ion balance of rice seedlings under salt stress.BMC plant biology · 2026Article
- Combined application of 5-ALA and nitric oxide improves lead detoxification and antioxidant defense in barley.Biodegradation · 2026Article
- PO Film: An Effective Strategy for Alleviating Leaf Photo-Oxidative Damage and Boosting Photosynthesis in Potted Tree Peony Under Summer Light and Temperature Stress.Plants (Basel, Switzerland) · 2026Article
- Changes in biochemical compositions and salinity tolerance responses of different bread wheat varieties cultivated in an arid and semi-arid climate.Scientific reports · 2025Article
- Metabolic activities, biochemical, and physiological processes in Mentha pulegium L. induced by drought stress and application of 5-aminolevulinic acidf.BMC plant biology · 2025Article
- 5-Aminolevulinic acid improves strawberry salt tolerance through a NO-HJournal of advanced research · 2025Article
- Metabolomic Profiling Identifies Key Metabolites and Defense Pathways inInternational journal of molecular sciences · 2025Article
- Evaluate the physiological role of tetrapyrroles precursor on growth, yield and some biochemical composition of two cultivars of Vicia faba L.BMC plant biology · 2025Article
- TOR Mediates Stress Responses Through Global Regulation of Metabolome in Plants.International journal of molecular sciences · 2025Review
- Exogenous 5-aminolevulinic acid enhanced saline-alkali tolerance in pepper seedlings by regulating photosynthesis, oxidative damage, and glutathione metabolism.Plant cell reports · 2024Article
- Targeted regulation of 5-aminolevulinic acid enhances flavonoids, anthocyanins and proanthocyanidins accumulation in Vitis davidii callus.BMC plant biology · 2024Article
- Biosynthesis and Extraction of Chlorophyll, Carotenoids, Anthocyanins, and Betalaine In Vivo and In Vitro.Current issues in molecular biology · 2024Review
- Coordinated wound responses in a regenerative animal-algal holobiont.Nature communications · 2024Article
- On the Possibility of Using 5-Aminolevulinic Acid in the Light-Induced Destruction of Microorganisms.International journal of molecular sciences · 2024Review
- 5-Aminolevulinic acid improves cold resistance through regulation of SlMYB4/SlMYB88-SlGSTU43 module to scavenge reactive oxygen species in tomato.Horticulture research · 2024Article
- MeJA-mediated enhancement of salt-tolerance of Populus wutunensis by 5-aminolevulinic acid.BMC plant biology · 2023Article
- 5-Aminolevulinic Acid Induces Chromium [Cr(VI)] Tolerance in Tomatoes by Alleviating Oxidative Damage and Protecting Photosystem II: A Mechanistic Approach.Plants (Basel, Switzerland) · 2023Article
- The 5-Aminolevulinic Acid (5-ALA) Supplement Enhances PSII Photochemical Activity and Antioxidant Activity in the Late Growth Promotion ofPlants (Basel, Switzerland) · 2022Article
- Evolutionary Trend Analysis of Research on 5-ALA Delivery and Theranostic Applications Based on a Scientometrics Study.Pharmaceutics · 2022Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Priming is an adaptive strategy that improves plant defenses against biotic and abiotic stresses. Stimuli from chemicals, abiotic cues, and pathogens can trigger the establishment of priming state. Priming with 5-aminolevulinic acid (ALA), a potential plant growth regulator, can enhance plant tolerance to the subsequent abiotic stresses, including salinity, drought, heat, cold, and UV-B. However, the molecular mechanisms underlying the remarkable effects of ALA priming on plant physiology remain to be elucidated. Here, we summarize recent progress made in the stress tolerance conferred by ALA priming in plants and provide the underlying molecular and physiology mechanisms of this phenomenon. Priming with ALA results in changes at the physiological, transcriptional, metabolic, and epigenetic levels, and enhances photosynthesis and antioxidant capacity, as well as nitrogen assimilation, which in turn increases the resistance of abiotic stresses. However, the signaling pathway of ALA, including receptors as well as key components, is currently unknown, which hinders the deeper understanding of the defense priming caused by ALA. In the future, there is an urgent need to reveal the molecular mechanisms by which ALA regulates plant development and enhances plant defense with the help of forward genetics, multi-omics technologies, as well as genome editing technology.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.