Evidence map›Paper›PMID 35054779›Full record

ReviewInternational journal of molecular sciences2022

Multiple Faces of the Glioblastoma Microenvironment.

Alina Simona Șovrea, Bianca Boșca, Carmen Stanca Melincovici, Anne-Marie Constantin, Andreea Crintea, Mariana Mărginean, Eleonora Dronca, Mihaela Elena Jianu, Rada Suflețel, Diana Gonciar and 2 more

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Review
  2. Frontiers in immunology · 2026
    Article
  3. Article
  4. DUSP8 as a regulator of glioblastoma stem-like cell contribution to tumor vascularization.Journal of experimental & clinical cancer research : CR · 2025
    Article
  5. Article
  6. Review
  7. Review
  8. Functional 3D Human Neuron-Glioblastoma Model Reveals Cellular Interactions Enabling Drug Safety Assessments.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2025
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Review
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Alina Simona ȘovreaHistology Discipline, Morphological Sciences Department, Iuliu Hatieganu University of Medicine and Pharmacy, 400000 Cluj-Napoca, Romania.
Bianca BoșcaHistology Discipline, Morphological Sciences Department, Iuliu Hatieganu University of Medicine and Pharmacy, 400000 Cluj-Napoca, Romania.
Carmen Stanca MelincoviciHistology Discipline, Morphological Sciences Department, Iuliu Hatieganu University of Medicine and Pharmacy, 400000 Cluj-Napoca, Romania.ORCID 0000-0002-2757-2565
Anne-Marie ConstantinHistology Discipline, Morphological Sciences Department, Iuliu Hatieganu University of Medicine and Pharmacy, 400000 Cluj-Napoca, Romania.
Andreea CrinteaMedical Biochemistry Discipline, Molecular Sciences Department, Iuliu Hatieganu University of Medicine and Pharmacy, 400000 Cluj-Napoca, Romania.
Mariana MărgineanHistology Discipline, Morphological Sciences Department, Iuliu Hatieganu University of Medicine and Pharmacy, 400000 Cluj-Napoca, Romania.
Eleonora DroncaMedical Genetics Discipline, Molecular Sciences Department, Iuliu Hatieganu University of Medicine and Pharmacy, 400000 Cluj-Napoca, Romania.
Mihaela Elena JianuHistology Discipline, Morphological Sciences Department, Iuliu Hatieganu University of Medicine and Pharmacy, 400000 Cluj-Napoca, Romania.
Rada SuflețelHistology Discipline, Morphological Sciences Department, Iuliu Hatieganu University of Medicine and Pharmacy, 400000 Cluj-Napoca, Romania.
Diana GonciarPathological Anatomy Discipline, Morphological Sciences Department, Iuliu Hatieganu University of Medicine and Pharmacy, 400000 Cluj-Napoca, Romania.
Maria BungărdeanPathological Anatomy Discipline, Morphological Sciences Department, Iuliu Hatieganu University of Medicine and Pharmacy, 400000 Cluj-Napoca, Romania.
Carmen-Bianca CriviiAnatomy and Embryology Discipline, Morphological Sciences Department, Iuliu Hatieganu University of Medicine and Pharmacy, 400000 Cluj-Napoca, Romania.ORCID 0000-0001-5275-5753

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The tumor microenvironment is a highly dynamic accumulation of resident and infiltrating tumor cells, responsible for growth and invasion. The authors focused on the leading-edge concepts regarding the glioblastoma microenvironment. Due to the fact that the modern trend in the research and treatment of glioblastoma is represented by multiple approaches that target not only the primary tumor but also the neighboring tissue, the study of the microenvironment in the peritumoral tissue is an appealing direction for current and future therapies.

Indexed as

Tumor MicroenvironmentGlioblastomaHumansglioblastomaintercellular communicationmicroenvironment

Identifiers

PMID35054779
PMCPMC8775531

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.