Evidence map›Paper›PMID 35054770›Full record

ReviewInternational journal of molecular sciences2022

Plant-Derived Antioxidants: Significance in Skin Health and the Ageing Process.

Monika Michalak

Registry-linked trialOpen access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05986799 (A Randomized, Controlled Trial of Efficacy of Amway Herbal Drink to Improve Skin Anti-aging), which is not on this map. Cited by 163 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
163citing papers in PubMed, 2 pooled it
76.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05986799 naunknown statusnot on this mapstarted 2023, after this paper: background citation

A Randomized, Controlled Trial of Efficacy of Amway Herbal Drink to Improve Skin Anti-aging

TypeinterventionalSponsorAmway (China) R&D CenterRan2023 to 2023Enrolled30ConditionsSkin Laxity, Skin LinesArmsAmway Herbal Drink, Placebo Drink
3 · Its place in the literature

Who cites it

163 citing papers in PubMed, 2 syntheses or guidelines pooled it, 399 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Molecular Targets in Modern Cosmetic Science.Molecules (Basel, Switzerland) · 2026
    Review
  6. Review
  7. Article
  8. Article
  9. Pharmaceuticals (Basel, Switzerland) · 2026
    Review
  10. Kuwanon A fromAntioxidants (Basel, Switzerland) · 2026
    Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Observational
  16. Phytochemical Profile and Bioactive Potential ofCurrent issues in molecular biology · 2026
    Article
  17. Review
  18. International journal of molecular sciences · 2026
    Article
  19. Pharmaceuticals (Basel, Switzerland) · 2026
    Article
  20. Article

103 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Monika MichalakDepartment of Dermatology, Cosmetology and Aesthetic Surgery, Collegium Medicum, Jan Kochanowski University, IX Wieków Kielc 19, 35-317 Kielce, Poland.ORCID 0000-0003-0471-3561
Jan Kochanowski University · PL

Funding

Minister of Science and Higher Education under the name "Regional Initiative of Excellence" in 2019-2022 024/RID/2018/19
6 · The paper itself

Abstract

Natural substances have traditionally been used in skin care for centuries. There is now an ongoing search for new natural bioactives that not only promote skin health but also protect the skin against various harmful factors, including ultraviolet radiation and free radicals. Free radicals, by disrupting defence and restoration mechanisms, significantly contribute to skin damage and accelerate ageing. Natural compounds present in plants exhibit antioxidant properties and the ability to scavenge free radicals. The increased interest in plant chemistry is linked to the growing interest in plant materials as natural antioxidants. This review focuses on aromatic and medicinal plants as a source of antioxidant substances, such as polyphenols, tocopherols, carotenoids, ascorbic acid, and macromolecules (including polysaccharides and peptides) as well as components of essential oils, and their role in skin health and the ageing process.

Indexed as

AgingAnimalsAntioxidantsAscorbic AcidCarotenoidsHumansOxidative StressPhytochemicalsPolyphenolsSkinTocopherolsAntioxidantsAscorbic AcidCarotenoidsPhytochemicalsPolyphenolsTocopherolsantioxidantsascorbic acidcarotenoidsessential oilsmacromoleculesnatural compoundsphytochemicalspolyphenolsskintocopherols

Identifiers

PMID35054770
PMCPMC8776015
OpenAlexW4205209788

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.