Evidence map›Paper›PMID 35054731›Full record

ArticlePolymers2022

The Unique Carboxymethyl Fenugreek Gum Gel Loaded Itraconazole Self-Emulsifying Nanovesicles for Topical Onychomycosis Treatment.

Ali Alqahtani, Bhavana Raut, Shagufta Khan, Jamal Moideen Muthu Mohamed, Adel Al Fatease, Taha Alqahtani, Ali Alamri, Fazil Ahmad, Venkatesan Krishnaraju

Abstract read
In one paragraph

Article in Polymers, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Polymeric ethosomal gel loaded with nimodipine: Optimisation, pharmacokinetic and histopathological analysis.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2022
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Development of Atorvastatin Calcium Biloaded Capsules for Oral Administration of Hypercholesterolemia.Evidence-based complementary and alternative medicine : eCAM · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Ali AlqahtaniDepartment of Pharmacology, College of Pharmacy, King Khalid University, Guraiger, Abha 62529, Saudi Arabia.ORCID 0000-0002-2240-4757
Bhavana RautInstitute of Pharmaceutical Education and Research, Borgaon (Meghe) Wardha, Wardha 442001, India.
Shagufta KhanInstitute of Pharmaceutical Education and Research, Borgaon (Meghe) Wardha, Wardha 442001, India.
Jamal Moideen Muthu MohamedCollege of Pharmacy, Shri Indra Ganesan Institute of Medical Science, Tiruchirapalli 620012, India.ORCID 0000-0001-6362-8629
Adel Al FateaseDepartment of Pharmaceutics, College of Pharmacy, King Khalid University, Guraiger, Abha 62529, Saudi Arabia.ORCID 0000-0002-4608-5949
Taha AlqahtaniDepartment of Pharmacology, College of Pharmacy, King Khalid University, Guraiger, Abha 62529, Saudi Arabia.ORCID 0000-0003-4017-8754
Ali AlamriDepartment of Pharmaceutics, College of Pharmacy, King Khalid University, Guraiger, Abha 62529, Saudi Arabia.ORCID 0000-0001-6790-2226
Fazil AhmadDepartment of Anesthesia Technology, College of Applied Medical Sciences in Jubail, Imam Abdulrahman Bin Faisal University, Dammam 34212, Saudi Arabia.
Venkatesan KrishnarajuDepartment of Pharmacology, College of Pharmacy, King Khalid University, Guraiger, Abha 62529, Saudi Arabia.ORCID 0000-0003-2853-5907

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The novel itraconazole (ITZ) nail penetration enhancing self-emulsifying nanovesicles (ITZ-nPEVs) loaded in carboxymethyl fenugreek gum (CMFG) gel circumvent the systemic onychomycosis treatment. The ITZ-nPEVs were prepared by the thin film hydration technique, and the particle size (PS), zeta potential (ZP), drug content (DC), entrapment efficiency (% EE), deformity index (DI), viscosity, morphology, and physical stability of the ITZ-nPEVs were measured. In terms of nail hydration, transungual drug absorption, and antifungal efficacy against

Indexed as

anti-fungalitraconazoleonychomycosisself-emulsifying nanovesiclestransungual

Identifiers

PMID35054731
PMCPMC8779379

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.