Evidence map›Paper›PMID 35054631›Full record

ArticlePolymers2022

Fabrication of Low-Fouling Surfaces on Alkyne-Functionalized Poly-(p-xylylenes) Using Click Chemistry.

Pei-Ju Chen, Hsien-Yeh Chen, Wei-Bor Tsai

Abstract read
In one paragraph

Article in Polymers, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Clicking acylgermanes: modular access to photoinitiators for visible-light photopolymerization.Organic chemistry frontiers : an international journal of organic chemistry · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Pei-Ju ChenDepartment of Chemical Engineering, National Taiwan University, 1, Roosevelt Rd., Sec. 4, Taipei 10617, Taiwan.
Hsien-Yeh ChenDepartment of Chemical Engineering, National Taiwan University, 1, Roosevelt Rd., Sec. 4, Taipei 10617, Taiwan.ORCID 0000-0001-5956-6680
Wei-Bor TsaiDepartment of Chemical Engineering, National Taiwan University, 1, Roosevelt Rd., Sec. 4, Taipei 10617, Taiwan.ORCID 0000-0002-2316-5751

Funding

Ministry of Science and Technology of Taiwan MOST 107-3017-F-002-001 and 106-2221-E-002-166
6 · The paper itself

Abstract

A facial, versatile, and universal method that breaks the substrate limits is desirable for antifouling treatment. Thin films of functional poly-p-xylylenes (PPX) that are deposited using chemical vapor deposition (CVD) provide a powerful platform for surface immobilization of molecules. In this study, we prepared an alkyne-functionalized PPX coating on which poly (sulfobetaine methacrylate-co-Az) could be conjugated via click chemistry. We found that the conjugated polymers were very stable and inhibited cell adhesion and protein adsorption effectively. The same conjugation strategy could also be applied to conjugate azide-containing poly (ethylene glycol) and poly (NIPAAm). The results indicate that our method provides a simple and robust tool for fabricating antifouling surfaces on a wide range of substrates using CVD technology of functionalized poly (p-xylylenes) for biosensor, diagnostics, immunoassay, and other biomaterial applications.

Indexed as

anti-foulingchemical vapor depositionclick chemistrypoly-(p-xylylene)polysulfobetainethermo-responsive

Identifiers

PMID35054631
PMCPMC8780154

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.