Evidence map›Paper›PMID 35054525›Full record

ArticleLife (Basel, Switzerland)2022

Epidermal Barrier Function and Skin Homeostasis in Atopic Dermatitis: The Impact of Age.

Trinidad Montero-Vilchez, Carlos Cuenca-Barrales, Juan-Angel Rodriguez-Pozo, Pablo Diaz-Calvillo, Jesús Tercedor-Sanchez, Antonio Martinez-Lopez, Alejandro Molina-Leyva, Salvador Arias-Santiago

Open access · goldAbstract read
In one paragraph

Article in Life (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
8.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 41 citations in OpenAlex.

  1. Trial
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  7. Article
  8. Microenvironmental host-microbe interactions in chronic inflammatory skin diseases.APMIS : acta pathologica, microbiologica, et immunologica Scandinavica · 2024
    Review
  9. Article
  10. Article
  11. Article
  12. Research Progress in Skin Aging and Immunity.International journal of molecular sciences · 2024
    Review
  13. Review
  14. Article
  15. Review
  16. Article
  17. Article
  18. Contributions of renal water loss and skin water conservation to blood pressure elevation in spontaneously hypertensive rats.Hypertension research : official journal of the Japanese Society of Hypertension · 2023
    Article
  19. Article
  20. The Effect of Sunscreens on the Skin Barrier.Life (Basel, Switzerland) · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Trinidad Montero-VilchezDermatology Department, Hospital Universitario Virgen de las Nieves, Avenida de Madrid, 15, 18012 Granada, Spain.ORCID 0000-0003-4035-7955
Carlos Cuenca-BarralesDermatology Department, Hospital Universitario Virgen de las Nieves, Avenida de Madrid, 15, 18012 Granada, Spain.ORCID 0000-0001-7579-4931
Juan-Angel Rodriguez-PozoDermatology Department, Hospital Universitario Virgen de las Nieves, Avenida de Madrid, 15, 18012 Granada, Spain.
Pablo Diaz-CalvilloDermatology Department, Hospital Universitario Virgen de las Nieves, Avenida de Madrid, 15, 18012 Granada, Spain.
Jesús Tercedor-SanchezDermatology Department, Hospital Universitario Virgen de las Nieves, Avenida de Madrid, 15, 18012 Granada, Spain.ORCID 0000-0002-1548-594X
Antonio Martinez-LopezDermatology Department, Hospital Universitario Virgen de las Nieves, Avenida de Madrid, 15, 18012 Granada, Spain.
Alejandro Molina-LeyvaDermatology Department, Hospital Universitario Virgen de las Nieves, Avenida de Madrid, 15, 18012 Granada, Spain.ORCID 0000-0001-6882-2113
Salvador Arias-SantiagoDermatology Department, Hospital Universitario Virgen de las Nieves, Avenida de Madrid, 15, 18012 Granada, Spain.ORCID 0000-0002-4186-1435
Instituto de Investigación Biosanitaria de Granada · ESHospital Universitario Virgen de las Nieves · ESUniversidad de Granada · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Skin is damaged in atopic dermatitis (AD) patients. Age is also believed to have a negative effect on epidermal barrier function. The aim of this study was to investigate skin barrier function changes with age in AD patients. A cross-sectional study was conducted including 162 participants, 81 AD patients and 81 healthy volunteers. Skin barrier function parameters, such as transepidermal water loss (TEWL), erythema, temperature, stratum corneum hydration (SCH), pH, and elasticity, were evaluated. Healthy volunteers were evaluated on the volar forearm. AD patients were measured on two regions: on an eczematous lesion on the volar forearm and on a non-involved area 5 cm from the affected area. TEWL was lower on healthy skin than uninvolved AD skin (9.98 vs. 25.51 g·m

Indexed as

agingatopic dermatitisskin barrierstratum corneum

Identifiers

PMID35054525
PMCPMC8779900
OpenAlexW4205765882

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.