Evidence map›Paper›PMID 35054522›Full record

ArticleLife (Basel, Switzerland)2022

Ex Vivo Effect of Novel Lipophosphonoxins on Root Canal Biofilm Produced by

Yuliya Morozova, Iva Voborná, Radovan Žižka, Kateřina Bogdanová, Renata Večeřová, Dominik Rejman, Milan Kolář, Duy Dinh Do Pham, Pavel Holík, Roman Moštěk and 2 more

Open access · goldAbstract read
In one paragraph

Article in Life (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Yuliya MorozovaInstitute of Dentistry and Oral Sciences, Faculty of Medicine and Dentistry, Palacký University, Palackého 12, 772 00 Olomouc, Czech Republic.
Iva VobornáInstitute of Dentistry and Oral Sciences, Faculty of Medicine and Dentistry, Palacký University, Palackého 12, 772 00 Olomouc, Czech Republic.
Radovan ŽižkaInstitute of Dentistry and Oral Sciences, Faculty of Medicine and Dentistry, Palacký University, Palackého 12, 772 00 Olomouc, Czech Republic.
Kateřina BogdanováDepartment of Microbiology, Faculty of Medicine and Dentistry, Palacký University, Hněvotínská 3, 775 15 Olomouc, Czech Republic.
Renata VečeřováDepartment of Microbiology, Faculty of Medicine and Dentistry, Palacký University, Hněvotínská 3, 775 15 Olomouc, Czech Republic.
Dominik RejmanInstitute of Organic Chemistry and Biochemistry, Czech Academy of Sciences, Fleming Square 542/2, 160 00 Prague, Czech Republic.
Milan KolářDepartment of Microbiology, Faculty of Medicine and Dentistry, Palacký University, Hněvotínská 3, 775 15 Olomouc, Czech Republic.ORCID 0000-0003-4621-8868
Duy Dinh Do PhamInstitute of Organic Chemistry and Biochemistry, Czech Academy of Sciences, Fleming Square 542/2, 160 00 Prague, Czech Republic.
Pavel HolíkInstitute of Dentistry and Oral Sciences, Faculty of Medicine and Dentistry, Palacký University, Palackého 12, 772 00 Olomouc, Czech Republic.
Roman MoštěkInstitute of Dentistry and Oral Sciences, Faculty of Medicine and Dentistry, Palacký University, Palackého 12, 772 00 Olomouc, Czech Republic.
Matej RosaInstitute of Dentistry and Oral Sciences, Faculty of Medicine and Dentistry, Palacký University, Palackého 12, 772 00 Olomouc, Czech Republic.ORCID 0000-0003-0882-8438
Lenka PospíšilováInstitute of Dentistry and Oral Sciences, Faculty of Medicine and Dentistry, Palacký University, Palackého 12, 772 00 Olomouc, Czech Republic.
Palacký University Olomouc · CZCzech Academy of Sciences, Institute of Organic Chemistry and Biochemistry · CZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

(1) Background: The root canal system has complex anatomical and histological features that make it impossible to completely remove all bacteria by mechanical means only; they must be supplemented with disinfectant irrigation. Current disinfectants are unable to eliminate certain microorganisms that persist in the root canal, resulting in treatment failure. At the Institute of Organic Chemistry and Biochemistry, Prague, novel substances with the bactericidal effect, termed lipophosphonoxins (LPPOs), have been discovered. The aim of this pilot study was to investigate the ex vivo effects of second- and third-generation LPPOs on

Indexed as

biofilmchlorhexidine digluconateEDTAE. faecalislipophosphonoxinsroot canalsodium hypochlorite

Identifiers

PMID35054522
PMCPMC8781533
OpenAlexW4206331841

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.