Evidence map›Paper›PMID 35054521›Full record

ArticleLife (Basel, Switzerland)2022

RETRACTED: Assessment of 2-Pentadecyl-2-oxazoline Role on Lipopolysaccharide-Induced Inflammation on Early Stage Development of Zebrafish (Danio rerio)

Davide Di Paola, Sabrina Natale, Enrico Gugliandolo, Marika Cordaro, Rosalia Crupi, Rosalba Siracusa, Ramona D'Amico, Roberta Fusco, Daniela Impellizzeri, Salvatore Cuzzocrea and 3 more

RetractedOpen access · goldAbstract readRetracted Publication
In one paragraph

Article in Life (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
  2. Effects of carnosine on the embryonic development and TiOFrontiers in veterinary science · 2023
    Article
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  7. Natural Compounds Such asBiomedicines · 2022
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors at 1 institution in 2 countries.

Davide Di PaolaDepartment of Chemical, Biological, Pharmaceutical and Environmental Science, University of Messina, 98166 Messina, Italy.ORCID 0000-0002-7563-9832
Sabrina NataleDepartment of Chemical, Biological, Pharmaceutical and Environmental Science, University of Messina, 98166 Messina, Italy.
Enrico GugliandoloDepartment of Veterinary Science, University of Messina, 98166 Messina, Italy.ORCID 0000-0001-6840-3154
Marika CordaroDepartment of Biomedical and Dental Sciences and Morphofunctional Imaging, University of Messina, 98166 Messina, Italy.ORCID 0000-0002-3980-0043
Rosalia CrupiDepartment of Veterinary Science, University of Messina, 98166 Messina, Italy.ORCID 0000-0002-7629-3132
Rosalba SiracusaDepartment of Chemical, Biological, Pharmaceutical and Environmental Science, University of Messina, 98166 Messina, Italy.ORCID 0000-0001-7868-2505
Ramona D'AmicoDepartment of Chemical, Biological, Pharmaceutical and Environmental Science, University of Messina, 98166 Messina, Italy.ORCID 0000-0003-0389-3871
Roberta FuscoDepartment of Chemical, Biological, Pharmaceutical and Environmental Science, University of Messina, 98166 Messina, Italy.ORCID 0000-0003-0223-1403
Daniela ImpellizzeriDepartment of Chemical, Biological, Pharmaceutical and Environmental Science, University of Messina, 98166 Messina, Italy.ORCID 0000-0001-9492-3161
Salvatore CuzzocreaDepartment of Chemical, Biological, Pharmaceutical and Environmental Science, University of Messina, 98166 Messina, Italy.ORCID 0000-0001-6131-3690
Nunziacarla SpanòDepartment of Biomedical and Dental Sciences and Morphofunctional Imaging, University of Messina, 98166 Messina, Italy.ORCID 0000-0002-8360-4795
Fabio MarinoDepartment of Chemical, Biological, Pharmaceutical and Environmental Science, University of Messina, 98166 Messina, Italy.
Alessio Filippo PeritoreDepartment of Chemical, Biological, Pharmaceutical and Environmental Science, University of Messina, 98166 Messina, Italy.ORCID 0000-0001-8545-990X
University of Messina · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lipopolysaccharide (LPS), or bacterial endotoxin, is an important virulence factor in several human and animal pathologies. Oxazoline of Palmitoylethanolamide (PEAOXA) has shown strong anti-inflammatory activity in several animal models. LPS was applied for 24 h to zebrafish embryos to induce inflammation, and then the anti-inflammatory action of PEAOXA was evaluated for the first time in the zebrafish model (

Indexed as

apoptosiscytokinesinflammationPEAOXAzebrafish

Identifiers

PMID35054521
PMCPMC8781862
OpenAlexW4205696675

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.