Evidence map›Paper›PMID 35054453›Full record

ArticleLife (Basel, Switzerland)2022

Renoprotection of Selected Antioxidant-Rich Foods (Water Spinach and Red Grape) and Probiotics in Gentamicin-Induced Nephrotoxicity and Oxidative Stress in Rats.

Sneha Sarwar, Md Jamal Hossain, Nafis Md Irfan, Tamima Ahsan, Md Saidul Arefin, Arebia Rahman, Abdullah Alsubaie, Badr Alharthi, Mayeen Uddin Khandaker, David A Bradley and 2 more

Open access · goldAbstract read
In one paragraph

Article in Life (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
5.4field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 31 citations in OpenAlex.

  1. Article
  2. Article
  3. Nephroprotection of Wood Apple (Journal of nutrition and metabolism · 2025
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  4. Review
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  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Cardioprotection of Water Spinach (Nutrition and metabolic insights · 2023
    Article
  15. Article
  16. Review
  17. Phenolic Constituents fromMolecules (Basel, Switzerland) · 2022
    Article
  18. Chemical and Pharmacological Profiling ofMolecules (Basel, Switzerland) · 2022
    Article
  19. Phytochemical and Pharmacological Profiling ofEvidence-based complementary and alternative medicine : eCAM · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 8 institutions in 5 countries.

Sneha SarwarInstitute of Nutrition and Food Science, University of Dhaka, Dhaka 1000, Bangladesh.
Md Jamal HossainDepartment of Pharmacy, State University of Bangladesh, 77 Satmasjid Road, Dhanmondi, Dhaka 1205, Bangladesh.ORCID 0000-0001-9706-207X
Nafis Md IrfanInstitute of Nutrition and Food Science, University of Dhaka, Dhaka 1000, Bangladesh.
Tamima AhsanInstitute of Nutrition and Food Science, University of Dhaka, Dhaka 1000, Bangladesh.
Md Saidul ArefinInstitute of Nutrition and Food Science, University of Dhaka, Dhaka 1000, Bangladesh.
Arebia RahmanDepartment of Pathology, Dhaka Medical College and Hospital, Dhaka 1000, Bangladesh.
Abdullah AlsubaieDepartment of Physics, College of Khurma, Taif University, P.O. Box 11099, Taif 21944, Saudi Arabia.
Badr AlharthiDepartment of Biology, University College of Al Khurmah, Taif University, PO. Box 11099, Taif 21944, Saudi Arabia.ORCID 0000-0003-4515-1171
Mayeen Uddin KhandakerCentre for Applied Physics and Radiation Technologies, School of Engineering and Technology, Sunway University, Bandar Sunway, Petaling Jaya 47500, Malaysia.ORCID 0000-0003-3772-294X
David A BradleyCentre for Applied Physics and Radiation Technologies, School of Engineering and Technology, Sunway University, Bandar Sunway, Petaling Jaya 47500, Malaysia.
Talha Bin EmranDepartment of Pharmacy, BGC Trust University Bangladesh, Chittagong 4381, Bangladesh.ORCID 0000-0003-3188-2272
Sheikh Nazrul IslamInstitute of Nutrition and Food Science, University of Dhaka, Dhaka 1000, Bangladesh.ORCID 0000-0001-7327-131X
University of Dhaka · BDTaif University · SABGC Trust University Bangladesh · BDDhaka Medical College and Hospital · BDState University of Bangladesh · BDSunway University · MYUniversity of Iowa · USUniversity of Surrey · GB

Funding

Taif University TURSP-2020/163
6 · The paper itself

Abstract

objectivesThe current study investigated the curative effects of two selected antioxidant-rich foods (water spinach and red grape) and probiotics on the kidney exposed to nephrotoxicity induced by gentamicin.

methodsA total of 30 Wistar Albino female rats equally divided into six groups were studied for seven days. Except for the normal control (NC) group, all groups received 80 mg/kg/day gentamicin (GEN) injection intra-peritoneally for seven days. NC and GEN groups received only regular diet. In the water spinach group (GEN + WS) and red grape (GEN + RG) groups, rats were provided with 20 g/rat/day of boiled water spinach and 5 mL/rat/day of red grape juice, respectively. The probiotic (GEN + P

resultsBoth antioxidant-rich foods and probiotic (P

conclusionThe current preclinical study suggests that the consumption of antioxidant-rich foods might be a promising fighting option against gentamycin-induced nephrotoxicity and oxidative stress. However, extensive studies and clinical monitoring are immediately required to determine the appropriate probiotic doses and mechanism of action for such effects.

Indexed as

gentamicin-induced nephropathynephroprotectionnitrosative stressoxidative stressprobioticsred grapewater spinach

Identifiers

PMID35054453
PMCPMC8780918
OpenAlexW4206080157

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.