Evidence map›Paper›PMID 35054416›Full record

ArticleLife (Basel, Switzerland)2021

HEK293T Cells with TFAM Disruption by CRISPR-Cas9 as a Model for Mitochondrial Regulation.

Vanessa Cristina de Oliveira, Kelly Cristine Santos Roballo, Clésio Gomes Mariano Junior, Sarah Ingrid Pinto Santos, Fabiana Fernandes Bressan, Marcos Roberto Chiaratti, Elena J Tucker, Erica E Davis, Jean-Paul Concordet, Carlos Eduardo Ambrósio

Open access · goldAbstract read
In one paragraph

Article in Life (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 4 countries.

Vanessa Cristina de OliveiraDepartment of Veterinary Medicine, Faculty of Animal Science and Food Engineering, University of São Paulo, São Paulo 13635-900, Brazil.
Kelly Cristine Santos RoballoDepartment of Veterinary Medicine, Faculty of Animal Science and Food Engineering, University of São Paulo, São Paulo 13635-900, Brazil.
Clésio Gomes Mariano JuniorDepartment of Veterinary Medicine, Faculty of Animal Science and Food Engineering, University of São Paulo, São Paulo 13635-900, Brazil.ORCID 0000-0002-4553-1097
Sarah Ingrid Pinto SantosDepartment of Veterinary Medicine, Faculty of Animal Science and Food Engineering, University of São Paulo, São Paulo 13635-900, Brazil.
Fabiana Fernandes BressanDepartment of Veterinary Medicine, Faculty of Animal Science and Food Engineering, University of São Paulo, São Paulo 13635-900, Brazil.ORCID 0000-0001-9862-5874
Marcos Roberto ChiarattiDepartment of Genetics and Evolution, Federal University of São Carlos, São Carlos 13565-905, Brazil.
Elena J TuckerMurdoch Children's Research Institute, Royal Children's Hospital, Melbourne 3052, Australia.ORCID 0000-0002-6380-5100
Erica E DavisStanley Manne Children's Research Institute, Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, IL 60611, USA.
Jean-Paul ConcordetLaboratoire Structure et Instabilité des Génomes, Museum National d'Histoire Naturelle, INSERM U1154, CNRS UMR7196, 75231 Paris, France.
Carlos Eduardo AmbrósioDepartment of Veterinary Medicine, Faculty of Animal Science and Food Engineering, University of São Paulo, São Paulo 13635-900, Brazil.ORCID 0000-0002-8224-5022
Universidade de São Paulo · BRCentre National de la Recherche Scientifique · FRNorthwestern University · USRoyal Children's Hospital · AUUniversidade Federal de São Carlos · BR

Funding

Australian National Health and Medical Research Council fellowship 1054432São Paulo Research Foundation grant #2017/08896-4São Paulo Research Foundation grant#2019/04442-4
6 · The paper itself

Abstract

The mitochondrial transcription factor A (

Indexed as

CRISPR-Cas9gene editingHEK293T cellsmitochondrial DNATFAM

Identifiers

PMID35054416
PMCPMC8779421
OpenAlexW4200190009

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.