Evidence map›Paper›PMID 35054412›Full record

ReviewLife (Basel, Switzerland)2021

Pediatric Neuromyelitis Optica Spectrum Disorder: Case Series and Literature Review.

Michela Ada Noris Ferilli, Roberto Paparella, Ilaria Morandini, Laura Papetti, Lorenzo Figà Talamanca, Claudia Ruscitto, Fabiana Ursitti, Romina Moavero, Giorgia Sforza, Samuela Tarantino and 3 more

Open access · goldAbstract readReview
In one paragraph

Review in Life (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 2 countries.

Michela Ada Noris FerilliNeuroscience Department, Bambino Gesù Children's Hospital IRCCS, 00165 Rome, Italy.
Roberto PaparellaDepartment of Maternal and Child Health and Urology, Sapienza University of Rome, 00165 Rome, Italy.ORCID 0000-0001-7020-1471
Ilaria MorandiniChild Neurology Unit, Systems Medicine Department, Tor Vergata University Hospital of Rome, 00165 Rome, Italy.
Laura PapettiNeuroscience Department, Bambino Gesù Children's Hospital IRCCS, 00165 Rome, Italy.
Lorenzo Figà TalamancaImaging Department, Bambino Gesù Children's Hospital IRCCS, 00165 Rome, Italy.
Claudia RuscittoChild Neurology Unit, Systems Medicine Department, Tor Vergata University Hospital of Rome, 00165 Rome, Italy.
Fabiana UrsittiNeuroscience Department, Bambino Gesù Children's Hospital IRCCS, 00165 Rome, Italy.
Romina MoaveroNeuroscience Department, Bambino Gesù Children's Hospital IRCCS, 00165 Rome, Italy.ORCID 0000-0002-6200-060X
Giorgia SforzaNeuroscience Department, Bambino Gesù Children's Hospital IRCCS, 00165 Rome, Italy.
Samuela TarantinoUnit of Clinical Psychology, Neuroscience Department, Bambino Gesù Children's Hospital IRCCS, 00165 Rome, Italy.
Martina Proietti ChecchiUnit of Clinical Psychology, Neuroscience Department, Bambino Gesù Children's Hospital IRCCS, 00165 Rome, Italy.
Federico VigevanoNeuroscience Department, Bambino Gesù Children's Hospital IRCCS, 00165 Rome, Italy.
Massimiliano ValerianiNeuroscience Department, Bambino Gesù Children's Hospital IRCCS, 00165 Rome, Italy.ORCID 0000-0001-6602-103X
Bambino Gesù Children's Hospital · ITUniversity of Rome Tor Vergata · ITSapienza University of Rome · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neuromyelitis Optica Spectrum Disorder (NMOSD) is a central nervous system (CNS) inflammatory demyelinating disease characterized by recurrent inflammatory events that primarily involve optic nerves and the spinal cord, but also affect other regions of the CNS, including hypothalamus, area postrema and periaqueductal gray matter. The aquaporin-4 antibody (AQP4-IgG) is specific for NMOSD. Recently, myelin oligodendrocyte glycoprotein antibodies (MOG-IgG) have been found in a group of AQP4-IgG negative patients. NMOSD is rare among children and adolescents, but early diagnosis is important to start adequate therapy. In this report, we present cases of seven pediatric patients with NMOSD and we review the clinical and neuroimaging characteristics, diagnosis, and treatment of NMOSD in children.

Indexed as

aquaporin-4 antibodychildrenlongitudinally extensive transverse myelitismyelin oligodendrocyte glycoprotein antibodiesneuromyelitis optica spectrum disorderoptic neuritis

Identifiers

PMID35054412
PMCPMC8779266
OpenAlexW4200440291

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.