Evidence map›Paper›PMID 35054391›Full record

ArticleDiagnostics (Basel, Switzerland)2022

AI Denoising Significantly Improves Image Quality in Whole-Body Low-Dose Computed Tomography Staging.

Andreas S Brendlin, David Plajer, Maryanna Chaika, Robin Wrazidlo, Arne Estler, Ilias Tsiflikas, Christoph P Artzner, Saif Afat, Malte N Bongers

Open access · goldAbstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
3.6field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 26 citations in OpenAlex.

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  5. State-of-the-Art Deep Learning CT Reconstruction Algorithms in Abdominal Imaging.Radiographics : a review publication of the Radiological Society of North America, Inc · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Andreas S BrendlinDepartment of Diagnostic and Interventional Radiology, Eberhard-Karls University, D-72076 Tuebingen, Germany.ORCID 0000-0002-5961-9727
David PlajerDepartment of Diagnostic and Interventional Radiology, Eberhard-Karls University, D-72076 Tuebingen, Germany.
Maryanna ChaikaDepartment of Diagnostic and Interventional Radiology, Eberhard-Karls University, D-72076 Tuebingen, Germany.ORCID 0000-0002-6582-5105
Robin WrazidloDepartment of Diagnostic and Interventional Radiology, Eberhard-Karls University, D-72076 Tuebingen, Germany.
Arne EstlerDepartment of Diagnostic and Interventional Radiology, Eberhard-Karls University, D-72076 Tuebingen, Germany.ORCID 0000-0002-1930-7497
Ilias TsiflikasDepartment of Diagnostic and Interventional Radiology, Eberhard-Karls University, D-72076 Tuebingen, Germany.
Christoph P ArtznerDepartment of Diagnostic and Interventional Radiology, Eberhard-Karls University, D-72076 Tuebingen, Germany.
Saif AfatDepartment of Diagnostic and Interventional Radiology, Eberhard-Karls University, D-72076 Tuebingen, Germany.ORCID 0000-0002-6861-6245
Malte N BongersDepartment of Diagnostic and Interventional Radiology, Eberhard-Karls University, D-72076 Tuebingen, Germany.
University of Tübingen · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

(1) Background: To evaluate the effects of an AI-based denoising post-processing software solution in low-dose whole-body computer tomography (WBCT) stagings; (2) Methods: From 1 January 2019 to 1 January 2021, we retrospectively included biometrically matching melanoma patients with clinically indicated WBCT staging from two scanners. The scans were reconstructed using weighted filtered back-projection (wFBP) and Advanced Modeled Iterative Reconstruction strength 2 (ADMIRE 2) at 100% and simulated 50%, 40%, and 30% radiation doses. Each dataset was post-processed using a novel denoising software solution. Five blinded radiologists independently scored subjective image quality twice with 6 weeks between readings. Inter-rater agreement and intra-rater reliability were determined with an intraclass correlation coefficient (ICC). An adequately corrected mixed-effects analysis was used to compare objective and subjective image quality. Multiple linear regression measured the contribution of "Radiation Dose", "Scanner", "Mode", "Rater", and "Timepoint" to image quality. Consistent regions of interest (ROI) measured noise for objective image quality; (3) Results: With good-excellent inter-rater agreement and intra-rater reliability (Timepoint 1: ICC ≥ 0.82, 95% CI 0.74-0.88; Timepoint 2: ICC ≥ 0.86, 95% CI 0.80-0.91; Timepoint 1 vs. 2: ICC ≥ 0.84, 95% CI 0.78-0.90; all

Indexed as

AI (artificial intelligence)computed tomographyimage quality enhancementprotectionradiationtumor staging

Identifiers

PMID35054391
PMCPMC8774552
OpenAlexW4206820676

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.