ArticleDiagnostics (Basel, Switzerland)2022
Isolated Splenic Metastasis of Primary Lung Cancer Presented as Metachronous Oligometastatic Disease-A Case Report.
Article in Diagnostics (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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6 citing papers in PubMed, 5 citations in OpenAlex.
- Combined Point Mutation in a Single Allele of the TP53 Gene Potentiates the Oncogenic and Transcriptional Properties of TP53 in Lung Cancer.International journal of biological sciences · 2026Article
- Isolated Metachronous Splenic Metastasis of Lung Adenocarcinoma: Long-Term Survival After Splenectomy.Case reports in oncological medicine · 2026Article
- Isolated Splenic Metastasis From Large-Cell Neuroendocrine Carcinoma of Lung: A Case Report.Cureus · 2024Article
- Laparoscopic approach in the treatment of splenic angiolipomatous hamartoma: the first report of a case.The Journal of international medical research · 2023Article
- The Rarity of Metastasis to the Spleen - a Phenomenon with an Unknown Mechanism.Bulletin of experimental biology and medicine · 2022Article
- Clinicopathological Features and Prognoses of Patients With Splenic Metastases From Breast Cancer: A Single-Centre, Retrospective Study.Cancer control : journal of the Moffitt Cancer CenterArticle
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8 authors at 3 institutions in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
Modern oncology practice and new antitumor drugs prolonged disease-free intervals in patients with lung cancer. Patients with distant metastatic disease are treated only with palliative intent. The International Association for the Study of Lung Cancer, in the 8th edition of the TNM classification, for the first time includes oligometastatic disease as a clinical state that describes the patients with distant metastasis, limited in number and organ sites, who may have more indolent biology. In this paper, we present a case of a 56-year-old man who was admitted to our clinic regarding a radiologically diagnosed splenic lesion of uncertain nature, and who underwent a left upper lobectomy for primary lung cancer 12 years before. After a detailed radiological diagnosis, it was concluded that it is highly suspected metastatic lesion of the spleen and the patient underwent a splenectomy. While no definitive protocols exist on the management of isolated splenic metastasis from lung cancer, splenectomy, in suitable patients, with reasonable survival expectations, improves patient disease-free survival and can prevent potentially life-threatening complications, such as splenic rupture.
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