Evidence map›Paper›PMID 35054371›Full record

ArticleDiagnostics (Basel, Switzerland)2022

Preliminary Clinical Experience with a Novel Optical-Ultrasound Imaging Device on Various Skin Lesions.

Gergely Csány, László Hunor Gergely, Norbert Kiss, Klára Szalai, Kende Lőrincz, Lilla Strobel, Domonkos Csabai, István Hegedüs, Péter Marosán-Vilimszky, Krisztián Füzesi and 2 more

Open access · goldAbstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.6field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
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  5. Review
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  7. Review
  8. Article
  9. Zinc, Copper, and Iron in Selected Skin Diseases.International journal of molecular sciences · 2024
    Review
  10. Article
  11. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Gergely CsányDermus Ltd., Sopron út 64, 1116 Budapest, Hungary.
László Hunor GergelyDepartment of Dermatology, Venereology and Dermatooncology, Semmelweis University, Mária utca 41, 1085 Budapest, Hungary.
Norbert KissDermus Ltd., Sopron út 64, 1116 Budapest, Hungary.ORCID 0000-0002-9947-1755
Klára SzalaiDepartment of Dermatology, Venereology and Dermatooncology, Semmelweis University, Mária utca 41, 1085 Budapest, Hungary.
Kende LőrinczDepartment of Dermatology, Venereology and Dermatooncology, Semmelweis University, Mária utca 41, 1085 Budapest, Hungary.ORCID 0000-0002-1861-1008
Lilla StrobelDermus Ltd., Sopron út 64, 1116 Budapest, Hungary.
Domonkos CsabaiDermus Ltd., Sopron út 64, 1116 Budapest, Hungary.
István HegedüsDermus Ltd., Sopron út 64, 1116 Budapest, Hungary.
Péter Marosán-VilimszkyDermus Ltd., Sopron út 64, 1116 Budapest, Hungary.
Krisztián FüzesiDermus Ltd., Sopron út 64, 1116 Budapest, Hungary.
Miklós SárdyDepartment of Dermatology, Venereology and Dermatooncology, Semmelweis University, Mária utca 41, 1085 Budapest, Hungary.ORCID 0000-0003-4306-5093
Miklós GyöngyDermus Ltd., Sopron út 64, 1116 Budapest, Hungary.
Semmelweis University · HUPázmány Péter Catholic University · HU

Funding

National Research, Development and Innovation Fund of Hungary ÚNKP-21-4-II-SE-10
6 · The paper itself

Abstract

A compact handheld skin ultrasound imaging device has been developed that uses co-registered optical and ultrasound imaging to provide diagnostic information about the full skin depth. The aim of the current work is to present the preliminary clinical results of this device. Using additional photographic, dermoscopic and ultrasonic images as reference, the images from the device were assessed in terms of the detectability of the main skin layer boundaries and characteristic image features. Combined optical-ultrasonic recordings of various types of skin lesions (melanoma, basal cell carcinoma, seborrheic keratosis, dermatofibroma, naevus, dermatitis and psoriasis) were taken with the device (N = 53) and compared with images captured with a reference portable skin ultrasound imager. The investigator and two additional independent experts performed the evaluation. The detectability of skin structures was over 90% for the epidermis, the dermis and the lesions. The morphological and echogenicity information observed for the different skin lesions were found consistent with those of the reference ultrasound device and relevant ultrasound images in the literature. The presented device was able to obtain simultaneous in-vivo optical and ultrasound images of various skin lesions. This has the potential for further investigations, including the preoperative planning of skin cancer treatment.

Indexed as

basal cell carcinomachronic skin inflammationdermatofibromadermatologymelanomanaevusportable ultrasoundseborrheic keratosisskin cancerskin ultrasound

Identifiers

PMID35054371
PMCPMC8774695
OpenAlexW4205281334

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.