Evidence map›Paper›PMID 35054333›Full record

ReviewDiagnostics (Basel, Switzerland)2022

Bias Investigation in Artificial Intelligence Systems for Early Detection of Parkinson's Disease: A Narrative Review.

Sudip Paul, Maheshrao Maindarkar, Sanjay Saxena, Luca Saba, Monika Turk, Manudeep Kalra, Padukode R Krishnan, Jasjit S Suri

Abstract readReview
In one paragraph

Review in Diagnostics (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Sudip PaulDepartment of Biomedical Engineering, North Eastern Hill University, Shillong 793022, India.ORCID 0000-0001-9856-539X
Maheshrao MaindarkarDepartment of Biomedical Engineering, North Eastern Hill University, Shillong 793022, India.
Sanjay SaxenaDepartment of CSE, International Institute of Information Technology, Bhuneshwar 751003, India.ORCID 0000-0002-8288-1010
Luca SabaDepartment of Radiology, University of Cagliari, 09121 Cagliari, Italy.
Monika TurkDepartment of Neurology, University Medical Centre Maribor, 1262 Maribor, Slovenia.
Manudeep KalraDepartment of Radiology, Harvard Medical School, Boston, MA 02115, USA.
Padukode R KrishnanNeurology Department, Fortis Hospital, Bangalore 560010, India.
Jasjit S SuriStroke Monitoring and Diagnostic Division, AtheroPoint™, Roseville, CA 95661, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and Motivation: Diagnosis of Parkinson's disease (PD) is often based on medical attention and clinical signs. It is subjective and does not have a good prognosis. Artificial Intelligence (AI) has played a promising role in the diagnosis of PD. However, it introduces bias due to lack of sample size, poor validation, clinical evaluation, and lack of big data configuration. The purpose of this study is to compute the risk of bias (RoB) automatically.

methodThe PRISMA search strategy was adopted to select the best 39 AI studies out of 85 PD studies closely associated with early diagnosis PD. The studies were used to compute 30 AI attributes (based on 6 AI clusters), using

resultThe ML and HM cutoffs were 3.50 and 2.33, respectively, which constituted 7, 13, and 6 for low-, moderate-, and high-bias studies. The best and worst architectures were "deep learning with sketches as outcomes" and "machine learning with Electroencephalography," respectively. We recommend (i) the usage of power analysis in big data framework, (ii) that it must undergo scientific validation using unseen AI models, and (iii) that it should be taken towards clinical evaluation for reliability and stability tests.

conclusionThe AI is a vital component for the diagnosis of early PD and the recommendations must be followed to lower the RoB.

Indexed as

AIbiascutoffmean scorePDrecommendations

Identifiers

PMID35054333
PMCPMC8774851

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.